Solprate Syrup

Introduction

Solprate is a prescription medication that contains the active ingredient Sodium Valproate. It is available as a syrup and is primarily used for the treatment of certain types of seizures, including absence seizures, tonic-clonic seizures, and complex partial seizures. Solprate is also indicated for the prevention of migraines in adults.

Uses

Solprate is prescribed to manage various conditions, including epilepsy and migraine headaches. It helps control seizures by stabilizing electrical activity in the brain and reducing the frequency and severity of seizures. Additionally, it may be used as a preventive therapy for migraines, helping to decrease the frequency and intensity of migraine attacks.

Dosage and Administration

The dosage of Solprate will vary depending on the individual patient’s age, weight, and specific medical condition. Follow the instructions provided by your healthcare provider. Generally, the starting dose for adults and children over 10 years of age is 15 mg/kg/day, divided into two or three doses. The dose may be gradually increased based on the patient’s response and tolerability. For children under 10 years of age, the dosage should be determined by the healthcare provider.

Solprate should be taken by mouth, with or without food. Use the provided measuring device to ensure accurate dosing. Shake the bottle well before each use. Do not stop or change the dosage of Solprate without consulting your healthcare provider.

Mechanism of Action

The active ingredient in Solprate, Sodium Valproate, works by increasing the levels of gamma-aminobutyric acid (GABA) in the brain. GABA is a neurotransmitter that helps to regulate the electrical activity of nerve cells. By enhancing GABA levels, Sodium Valproate helps to calm overactive electrical signals in the brain, thereby reducing the likelihood of seizures and migraines.

Side Effects

Common side effects may include drowsiness, dizziness, nausea, vomiting, abdominal pain, and changes in appetite. These side effects are usually mild and tend to improve as your body adjusts to the medication. If these side effects persist or worsen, inform your healthcare provider.

Serious side effects of Solprate are rare but may include liver problems, pancreatitis, and blood disorders. Seek immediate medical attention if you experience symptoms such as persistent vomiting, yellowing of the skin or eyes, dark urine, unexplained bruising or bleeding, or unusual fatigue.

Drug Interactions

inform your healthcare provider about all the medications you are taking, including over-the-counter drugs, herbal supplements, and vitamins. Solprate may interact with certain medications, such as other antiepileptic drugs, blood thinners, and medications that affect liver enzymes. These interactions can potentially alter the effectiveness or increase the risk of side effects. Your healthcare provider will carefully consider these interactions when prescribing Solprate and may adjust your dosage or recommend alternative medications if necessary.

Precautions

Before taking Solprate, inform your healthcare provider if you have a history of liver disease, pancreatitis, blood disorders, or if you are pregnant or planning to become pregnant. Sodium Valproate can cause birth defects, so use effective contraception during treatment. It is also recommended to avoid alcohol consumption while taking Solprate, as it may increase the risk of side effects.

Storage

Store Solprate at room temperature, away from direct sunlight and excessive heat. Keep the bottle tightly closed and out of reach of children. Do not use the medication if it has expired or if the liquid has changed in color or consistency. If you have any unused or expired medication, consult your pharmacist for proper disposal methods.

Patient Tips

• Take Solprate exactly as prescribed by your healthcare provider. Do not stop or change the dosage without consulting your doctor.
• Use the provided measuring device to ensure accurate dosing. Do not use household teaspoons or tablespoons.
• If you miss a dose, take it as soon as you remember. If it is close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule.
• Be aware that Solprate may cause drowsiness or dizziness. Avoid driving or operating machinery until you know how the medication affects you.
• Maintain regular follow-up appointments with your healthcare provider to monitor your response to the medication and to discuss any concerns or side effects you may be experiencing.
• If you have any questions or concerns about Solprate, consult your healthcare provider or pharmacist for further information.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Sodium valproate: medicine to treat epilepsy and bipolar disorder (NHS UK) [Accessed 20 Jun. 2024] (online) Available at:
• Dyzantil 200mg prolonged-release tablets (Health Professionals SmPC) Available at:
• Depakote Capsules Dosage Guide (Drugs.com) [Accessed 15 Jun. 2024] (online) Available at:
• Valproic Acid (MedlinePlus) [Accessed 27 Jun. 2024] (online) Available at:
• Kupferberg HJ. Sodium valproate. Adv Neurol. 1980;27:643-54. [Accessed 30 Jun. 2024] Available at: