Sorafenat 200mg Tablet

Introduction

Sorafenat is a prescription medication that contains the active ingredient Sorafenib. It is available under the brand name Sorafenat. This medication is primarily used for the treatment of certain types of cancer, including advanced renal cell carcinoma (a type of kidney cancer) and hepatocellular carcinoma (a type of liver cancer). It belongs to a class of medications called kinase inhibitors, which work by blocking the growth and spread of cancer cells.

Uses

Sorafenat is prescribed by healthcare professionals to treat specific types of cancer. It is commonly used in the treatment of advanced renal cell carcinoma, which is a type of kidney cancer that has spread to other parts of the body. Additionally, it is also used for the treatment of hepatocellular carcinoma, which is a type of liver cancer.

Dosage and Administration

The dosage of Sorafenat may vary depending on the specific type and stage of cancer being treated, as well as other individual factors. Follow the instructions provided by your healthcare professional regarding the dosage and duration of treatment.

Sorafenat is usually taken orally, with or without food. It is typically taken twice daily, approximately 12 hours apart. The tablets should be swallowed whole with a glass of water, and should not be crushed, chewed, or broken.

Take the medication exactly as prescribed by your healthcare professional. Do not adjust the dosage or stop taking the medication without consulting your doctor.

Mechanism of Action

The active ingredient in Sorafenat, Sorafenib, works by inhibiting the activity of certain proteins called kinases. These kinases play a role in the growth and spread of cancer cells. By blocking these kinases, Sorafenib helps to slow down or stop the growth of cancer cells, thereby reducing the size of tumors and preventing further spread of the disease.

Side Effects

be aware of these potential side effects and to seek medical attention if they occur or worsen. Common side effects may include:

• Fatigue
• Diarrhea
• Nausea
• Vomiting
• Loss of appetite
• Skin rash or dryness
• Hand-foot skin reaction (redness, swelling, or pain on the palms of the hands or soles of the feet)

In some cases, Sorafenat may also cause more serious side effects. These may include:

• Severe bleeding or bruising
• High blood pressure
• Liver problems
• Heart problems
• Kidney problems

If you experience any of these serious side effects, seek immediate medical attention.

Drug Interactions

Sorafenat may interact with other medications, including over-the-counter drugs, herbal supplements, and vitamins. Inform your healthcare professional about all the medications and supplements you are currently taking.

Some common and serious drug interactions with Sorafenat include:

• Warfarin and other blood thinners: Sorafenat may increase the risk of bleeding when taken with blood thinners.
• Rifampin and other enzyme-inducing drugs: These medications may reduce the effectiveness of Sorafenat.
• St. John’s wort: This herbal supplement may decrease the levels of Sorafenat in the body.

Discuss potential drug interactions with your healthcare professional before starting treatment with Sorafenat.

Precautions

Before taking Sorafenat, inform your healthcare professional about any medical conditions you have, including liver problems, heart problems, high blood pressure, bleeding disorders, or any allergies you may have.

Sorafenat is not recommended for use during pregnancy or while breastfeeding. It may harm the unborn baby or pass into breast milk and cause harm to the nursing infant. Discuss the risks and benefits of this medication with your healthcare professional if you are pregnant or breastfeeding.

Storage

Patient Tips

• Take Sorafenat exactly as prescribed by your healthcare professional.
• Do not adjust the dosage or stop taking the medication without consulting your doctor.
• If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule.
• attend all scheduled appointments with your healthcare professional for monitoring and evaluation of your treatment.
• If you experience any new or worsening symptoms, or if you have any concerns or questions about your treatment, contact your healthcare professional for guidance.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Nexavar 200mg film-coated tablets (Health Professionals SmPC) Available at:
• Sorafenib (Drugs.com) [Accessed 13 Jun. 2024] (online) Available at:
• sorafenib 200 mg tablet antineoplastic – protein-tyrosine kinase inhibitors (RX) [Accessed 16 Jun. 2024] (online) Available at:
• Sorafenib (MedlinePlus) [Accessed 13 Jun. 2024] (online) Available at:
• Abdelgalil AA, Alkahtani HM, Al-Jenoobi FI. Sorafenib. Profiles Drug Subst Excip Relat Methodol. 2019;44:239-266. doi: 10.1016/bs.podrm.2018.11.003. Epub 2019 Jan 18. [Accessed 22 Jun. 2024] Available at: