Sorifix Ointment

Introduction

Sorifix is a prescription medication that combines two active ingredients: Calcipotriol and Clobetasol. Calcipotriol is a synthetic form of vitamin D, while Clobetasol is a potent corticosteroid. This ointment is primarily used in the treatment of psoriasis, a chronic skin condition characterized by red, scaly patches on the skin.

Uses

Sorifix is prescribed for the management of plaque psoriasis in adults. Plaque psoriasis is the most common form of psoriasis and is characterized by the development of thick, red, and silvery patches of skin. It is used when other topical treatments have not provided adequate relief.

Dosage and Administration

The recommended dosage of Sorifix may vary depending on the severity of the psoriasis and the response to treatment. Generally, a thin layer of the ointment should be applied to the affected areas once daily. Follow the instructions provided by your healthcare professional and to avoid applying the ointment to healthy skin.

Mechanism of Action

Calcipotriol in Sorifix helps to normalize the rapid growth of skin cells associated with psoriasis. It works by binding to vitamin D receptors in the skin cells, which regulates their growth and differentiation. Clobetasol, on the other hand, is a potent corticosteroid that reduces inflammation and itching associated with psoriasis.

Side Effects

Common side effects may include skin irritation, burning or stinging sensation, dryness, redness, or itching at the application site. These side effects are usually mild and temporary. However, if you experience any severe or persistent side effects, such as skin thinning or changes in skin color, seek medical attention.

Drug Interactions

inform your healthcare professional about all the medications you are currently taking, including prescription, over-the-counter, and herbal products. Some medications may interact with Sorifix and affect its effectiveness or increase the risk of side effects. It is particularly important to avoid using other topical corticosteroids or vitamin D derivatives concurrently without medical supervision.

Precautions

Before using Sorifix, inform your healthcare professional if you have any known allergies or sensitivities to calcipotriol, clobetasol, or any other ingredients in the ointment. Disclose any other medical conditions you have, especially if you have a history of skin infections or if you are pregnant or breastfeeding.

Storage

Patient Tips

• Wash your hands thoroughly before and after applying Sorifix.
• Apply a thin layer of the ointment to the affected areas, avoiding healthy skin.
• Do not cover the treated area with bandages or dressings unless instructed by your healthcare professional.
• Avoid prolonged or excessive use of the ointment, as it may increase the risk of side effects.
• If you accidentally get the ointment in your eyes, rinse them thoroughly with water and seek medical advice if irritation persists.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Calcipotriol: a medicine to treat plaque psoriasis (NHS UK) [Accessed 17 Jun. 2024] (online) Available at:
• Calcipotriol 50 micrograms/ml Scalp Solution (Health Professionals SmPC) Available at:
• Dovonex Disease Interactions (Drugs.com) [Accessed 4 Jun. 2024] (online) Available at:
• clobetasol 0.05 % cream -gauze 4″ x 4″-silicone adhesive topical kit (RX) [Accessed 30 Jun. 2024] (online) Available at:
• Calcipotriene Topical (MedlinePlus) [Accessed 12 Jun. 2024] (online) Available at:
• Guilhou JJ. [Calcipotriol]. Ann Dermatol Venereol. 2001 Mar;128(3 Pt 1):229-37. [Accessed 13 Jun. 2024] Available at: