Introduction
Sulfawise is a prescription medication that contains Sulfasalazine as its active ingredient. It is available in tablet form and is commonly prescribed under this brand name.
Uses
Sulfawise is primarily prescribed for the treatment of inflammatory bowel disease (IBD), including ulcerative colitis and Crohn’s disease. It is also used to manage other conditions such as rheumatoid arthritis and juvenile rheumatoid arthritis.
Dosage and Administration
The dosage of Sulfawise may vary depending on the condition being treated and individual patient factors. Follow the instructions provided by your healthcare provider. Typically, the starting dose for adults is 500 mg to 1 gram taken orally, twice daily. The dose may be gradually increased to a maximum of 2 grams per day. For children, the dosage is based on their body weight.
Sulfawise should be taken with food to reduce the risk of stomach upset. Swallow the tablets whole and not crush or chew them, as this may affect the way the medication works.
Mechanism of Action
Sulfasalazine, the active ingredient in Sulfawise, works by reducing inflammation in the body. It is believed to work by inhibiting the production of certain chemicals that play a role in the inflammatory process. By reducing inflammation, it helps to alleviate the symptoms associated with inflammatory bowel disease and rheumatoid arthritis.
Side Effects
Common side effects may include nausea, vomiting, diarrhea, headache, and loss of appetite. These side effects are generally mild and temporary. However, if they persist or become bothersome, contact your healthcare provider.
In rare cases, Sulfawise may cause more serious side effects such as liver problems, blood disorders, and allergic reactions. Seek immediate medical attention if you experience any signs of a severe allergic reaction, such as difficulty breathing, swelling of the face or throat, or a rash.
Drug Interactions
inform your healthcare provider about all the medications you are taking, including prescription, over-the-counter, and herbal products. Some medications may interact with Sulfawise, potentially affecting its effectiveness or increasing the risk of side effects. Common drug interactions include warfarin, digoxin, and methotrexate.
Precautions
Before taking Sulfawise, inform your healthcare provider about any allergies or medical conditions you have, especially if you have a history of liver or kidney problems. Sulfawise may not be suitable for everyone and caution should be exercised in certain situations.
Sulfawise should not be taken by individuals who are allergic to sulfasalazine or any of its components. It is also contraindicated in individuals with a history of severe hypersensitivity reactions to sulfonamides or salicylates.
Storage
Sulfawise should be stored at room temperature, away from direct sunlight and moisture. Keep it out of reach of children and pets. Do not use the medication if it has expired or if the tablets appear discolored or damaged.
Patient Tips
- Take Sulfawise with food to reduce the risk of stomach upset.
- Follow the instructions provided by your healthcare provider regarding dosage and administration.
- Do not crush or chew the tablets; swallow them whole.
- If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule.
- Inform your healthcare provider about all the medications you are taking, including over-the-counter and herbal products.
- Report any unusual or persistent side effects to your healthcare provider.
- Store Sulfawise in a cool, dry place, away from children and pets.
Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.
References
- Sulfasalazine: an aminosalicylate that treats ulcerative colitis, Crohn’s disease and rheumatoid arthritis (NHS UK) [Accessed 25 Jun. 2024] (online) Available at:
- Salazopyrin En-Tabs 500 mg gastro-resistant tablets (Health Professionals SmPC) Available at:
- Sulfasalazine (Drugs.com) [Accessed 22 Jun. 2024] (online) Available at:
- sulfasalazine dr (RX) [Accessed 2 Jun. 2024] (online) Available at:
- Sulfasalazine (MedlinePlus) [Accessed 9 Jun. 2024] (online) Available at:
- Peppercorn MA. Sulfasalazine and related new drugs. J Clin Pharmacol. 1987 Apr;27(4):260-6. doi: 10.1002/j.1552-4604.1987.tb03009.x. [Accessed 13 Jun. 2024] Available at:
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