Introduction
Tamiflu is a prescription medication that contains the active ingredient Oseltamivir Phosphate. It is available in syrup form and is commonly used to treat and prevent influenza (commonly known as the flu).
Uses
Tamiflu is primarily prescribed for the treatment of influenza in patients aged 1 year and older. It is effective against both influenza A and B viruses. This medication works by inhibiting the growth and spread of the influenza virus in the body, helping to alleviate symptoms and reduce the duration of the illness.
Dosage and Administration
The recommended dosage of Tamiflu for adults and children aged 13 years and older is 75 mg twice daily for 5 days. For children aged 1 to 12 years, the dosage is based on their body weight. Follow the dosage instructions provided by your healthcare professional.
Tamiflu should be taken with food to help minimize potential stomach upset. The syrup can be measured using the provided dosing cup or an oral syringe. Shake the bottle well before each use to ensure proper mixing of the medication.
Mechanism of Action
Oseltamivir Phosphate, the active ingredient in Tamiflu, belongs to a class of medications called neuraminidase inhibitors. It works by inhibiting the activity of the neuraminidase enzyme, which is essential for the spread of the influenza virus in the body. By blocking this enzyme, Oseltamivir Phosphate helps to reduce the severity and duration of influenza symptoms.
Side Effects
Common side effects may include nausea, vomiting, headache, and diarrhea. These side effects are usually mild and go away on their own. However, if they persist or become severe, consult your healthcare professional.
In rare cases, Tamiflu may cause more serious side effects, such as allergic reactions or neuropsychiatric events. If you experience any signs of an allergic reaction, such as rash, itching, swelling, or difficulty breathing, seek immediate medical attention. Additionally, if you experience any unusual changes in mood or behavior, including confusion or self-harm ideation, discontinue the medication and contact your healthcare professional.
Drug Interactions
inform your healthcare professional about all medications you are currently taking, including over-the-counter drugs, herbal supplements, and vitamins. Certain medications may interact with Tamiflu, potentially affecting its effectiveness or increasing the risk of side effects. Some common and serious drug interactions include:
- Influenza Vaccines: Tamiflu may reduce the effectiveness of influenza vaccines. It is recommended to avoid receiving live attenuated influenza vaccines while taking this medication.
- Probenecid: Probenecid may increase the concentration of Oseltamivir Phosphate in the body, potentially leading to an increased risk of side effects. Your healthcare professional may need to adjust the dosage of Tamiflu if you are also taking probenecid.
Consult your healthcare professional before starting or stopping any medications while taking Tamiflu.
Precautions
Before taking Tamiflu, inform your healthcare professional about any medical conditions you have, especially:
- Allergies: If you have a known allergy to Oseltamivir Phosphate or any other ingredients in Tamiflu, you should avoid taking this medication.
- Renal Impairment: Tamiflu should be used with caution in patients with moderate to severe renal impairment. Your healthcare professional may need to adjust the dosage based on your kidney function.
- Pregnancy and Breastfeeding: The safety of Tamiflu during pregnancy and breastfeeding has not been established. Discuss the potential risks and benefits with your healthcare professional before using this medication.
Tamiflu may also interact with certain medications, including antibiotics, antiviral drugs, and medications that affect the liver. Disclose all medications you are taking to ensure safe and effective use of Tamiflu.
Storage
Tamiflu should be stored at room temperature, away from direct light and moisture. Keep the bottle tightly closed when not in use. Do not freeze the medication. Keep it out of reach of children and pets.
Patient Tips
- Take Tamiflu exactly as prescribed by your healthcare professional. Do not exceed the recommended dosage or duration of treatment.
- Remember to take the medication with food to minimize potential stomach upset.
- If you miss a dose, take it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule.
- Finish the full course of treatment, even if you start feeling better before completing the medication. This will help ensure the infection is fully treated.
- If you experience any unusual or concerning side effects while taking Tamiflu, contact your healthcare professional.
- Do not share your medication with others, as it has been prescribed specifically for you based on your medical condition and needs.
Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.
References
- Phosphate test (NHS UK) [Accessed 10 Jun. 2024] (online) Available at:
- Oseltamivir 30 mg Hard Capsules (Health Professionals SmPC) Available at:
- Oseltamivir (Drugs.com) [Accessed 12 Jun. 2024] (online) Available at:
- oseltamivir phosphate (RX) [Accessed 7 Jun. 2024] (online) Available at:
- What are Flu Antiviral Drugs (Centers for Disease Control and Prevention) [Accessed 23 Jun. 2024] (online) Available at:
- Shaim H, McCaffrey P, Trieu JA, DeAnda A, Yates SG. Evaluating the effects of oseltamivir phosphate on platelet counts: a retrospective review. Platelets. 2020 Nov 16;31(8):1080-1084. doi: 10.1080/09537104.2020.1714576. Epub 2020 Jan 13. [Accessed 10 Jun. 2024] Available at:
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