Temodal 250mg Capsule

Introduction

Temodal is a prescription medication that contains the active ingredient Temozolomide. It is available in capsule form and is used for the treatment of certain types of brain tumors, including glioblastoma multiforme and anaplastic astrocytoma.

Uses

Temodal is primarily prescribed for the treatment of brain tumors. It is commonly used in patients who have already received surgery and radiation therapy. This medication works by slowing down or stopping the growth of cancer cells in the brain.

Dosage and Administration

The dosage of Temodal may vary depending on the individual patient and the specific type of brain tumor being treated. Follow your healthcare provider’s instructions regarding the dosage and duration of treatment. Generally, the capsules are taken orally with a full glass of water, usually once a day. It is recommended to take the medication on an empty stomach, at least one hour before or two hours after a meal.

Mechanism of Action

Temozolomide, the active ingredient in Temodal, works by damaging the DNA in cancer cells. This prevents the cells from dividing and growing, ultimately leading to their destruction. By targeting cancer cells specifically, it helps to inhibit the growth and spread of brain tumors.

Side Effects

Common side effects may include nausea, vomiting, loss of appetite, fatigue, and hair loss. These side effects are usually temporary and can be managed with supportive care. However, if you experience severe or persistent side effects, consult your healthcare provider.

In some cases, Temodal may cause more serious side effects. These can include a decrease in blood cell counts, which may increase the risk of infection or bleeding, and liver problems. Contact your healthcare provider immediately if you experience any signs of infection, unusual bleeding or bruising, or yellowing of the skin or eyes.

Drug Interactions

inform your healthcare provider about all the medications you are currently taking, including prescription drugs, over-the-counter medications, and herbal supplements. Certain medications may interact with Temodal, potentially affecting its effectiveness or increasing the risk of side effects. Common drug interactions may include medications that affect liver function or those that increase the risk of bleeding. Always consult your healthcare provider for specific information about potential drug interactions.

Precautions

Before starting treatment with Temodal, discuss any medical conditions or allergies you have with your healthcare provider. This medication may not be suitable for everyone and there may be certain contraindications or precautions to consider. It is particularly important to inform your healthcare provider if you have a history of liver problems or a weakened immune system.

Temodal may also interact with other medications or substances, such as certain antibiotics or antifungal agents. Avoid or use caution when combining these medications to prevent potential interactions. Your healthcare provider will provide you with specific guidance regarding any precautions or interactions that may apply to your situation.

Storage

Temodal should be stored at room temperature, away from direct light and moisture. Keep the medication out of reach of children and pets. Do not store it in the bathroom or near the kitchen sink. Always check the expiration date on the packaging and properly dispose of any expired medication.

Patient Tips

• Take Temodal exactly as prescribed by your healthcare provider. Do not adjust the dosage or stop taking the medication without consulting your doctor.
• If you experience nausea or vomiting, try taking the medication with a light meal or snack. If the symptoms persist, speak to your healthcare provider as they may be able to prescribe medication to help manage these side effects.
• attend all scheduled appointments with your healthcare provider to monitor the effectiveness of the treatment and to check for any potential side effects.
• Use effective contraception during treatment with Temodal, as it may harm an unborn baby. If you are pregnant or planning to become pregnant, discuss the risks and benefits of this medication with your healthcare provider.
• If you miss a dose of Temodal, contact your healthcare provider for further instructions. Do not double the dose to make up for a missed dose.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Temodal Capsules (Health Professionals SmPC) Available at:
• Temozolomide oral/injection (Drugs.com) [Accessed 3 Jun. 2024] (online) Available at:
• temozolomide (RX) [Accessed 30 Jun. 2024] (online) Available at:
• Temozolomide (MedlinePlus) [Accessed 19 Jun. 2024] (online) Available at:
• Tomar MS, Kumar A, Srivastava C, Shrivastava A. Elucidating the mechanisms of Temozolomide resistance in gliomas and the strategies to overcome the resistance. Biochim Biophys Acta Rev Cancer. 2021 Dec;1876(2):188616. doi: 10.1016/j.bbcan.2021.188616. Epub 2021 Aug 20. [Accessed 29 Jun. 2024] Available at: