Introduction
Thrombophob is a topical medication that contains two active ingredients: Benzyl Nicotinate and Heparin. It is commonly prescribed for various conditions that involve pain, inflammation, and impaired blood circulation in the skin and underlying tissues.
Uses
Thrombophob is primarily used to relieve pain and improve blood circulation in conditions such as:
- Muscle and joint pain: It can help alleviate discomfort associated with conditions like sprains, strains, and arthritis.
- Bruises and hematomas: Thrombophob can help reduce swelling and promote healing in these types of injuries.
- Varicose veins: It may be used to alleviate symptoms like pain, swelling, and heaviness associated with varicose veins.
- Phlebitis: This medication can provide relief for inflammation of the veins.
- Chilblains: It can help alleviate the discomfort and inflammation associated with chilblains, which are localized painful swellings caused by exposure to cold.
Dosage and Administration
Thrombophob should be applied topically to the affected area. Follow these general dosage instructions:
- Adults: Apply a thin layer of the ointment to the affected area 2 to 3 times a day.
- Children: Use under the guidance of a healthcare professional.
Before applying the ointment, make sure the skin is clean and dry. Gently massage the ointment into the skin until it is fully absorbed. Avoid applying the ointment on broken or damaged skin.
Mechanism of Action
Thrombophob works through the combined action of its active ingredients, Benzyl Nicotinate and Heparin. Benzyl Nicotinate is a vasodilator, which means it helps widen blood vessels, improving blood flow to the affected area. Heparin, on the other hand, has anticoagulant properties that prevent the formation of blood clots. Together, these ingredients help reduce pain, inflammation, and promote healing.
Side Effects
Common side effects may include temporary skin redness, warmth, or itching at the site of application. These effects are usually mild and transient.
Serious side effects are rare but can occur. If you experience any of the following symptoms, please seek medical attention immediately:
- Severe skin irritation: This may include blistering, burning, or persistent redness.
- Allergic reaction: Signs of an allergic reaction may include rash, itching, swelling, dizziness, or difficulty breathing.
Drug Interactions
inform your healthcare provider about all the medications you are taking, including over-the-counter drugs, herbal supplements, and vitamins. Thrombophob may interact with certain medications, such as anticoagulants or other topical products. It is best to consult with a healthcare professional to ensure there are no potential drug interactions.
Precautions
Before using Thrombophob, consider the following precautions:
- Allergies: If you have a known allergy to Benzyl Nicotinate, Heparin, or any other ingredients in the ointment, avoid using this product.
- Pregnancy and breastfeeding: Consult with your healthcare provider before using Thrombophob if you are pregnant, planning to become pregnant, or breastfeeding.
- Open wounds or broken skin: Do not apply the ointment to open wounds or broken skin as it may cause irritation.
- Children: Use under the guidance of a healthcare professional for children.
Storage
Thrombophob should be stored at room temperature, away from direct sunlight and moisture. Keep it out of reach of children and pets. Do not use the ointment if it has passed the expiration date printed on the packaging.
Patient Tips
Here are some additional tips to help you use Thrombophob safely:
- Avoid applying the ointment near the eyes, mouth, or other mucous membranes.
- If you accidentally ingest the ointment or experience any unusual symptoms after application, seek medical attention.
- If your symptoms do not improve or worsen after a few days of using the ointment, consult your healthcare provider.
- Do not use the ointment on large areas of the body or for an extended period without medical advice.
Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.
References
- Benzoyl peroxide: a medicine to treat acne (NHS UK) [Accessed 12 Jun. 2024] (online) Available at:
- Heparin (Mucous) Injection BP 1,000 IU (Health Professionals SmPC) Available at:
- Benzyl Nicotinate (International database) (Drugs.com) [Accessed 30 Jun. 2024] (online) Available at:
- bd posiflush heparin lock (pf) syringe (RX) [Accessed 24 Jun. 2024] (online) Available at:
- How to give a heparin shot (MedlinePlus) [Accessed 13 Jun. 2024] (online) Available at:
- Tripathi PP, Kumawat V, Shankara NB. Blister formation at post donation phlebotomy site after topical application of combination of Benzyl Nicotinate and Heparin: An unpleasant post donation experience. Transfus Clin Biol. 2023 Feb;30(1):24-25. doi: 10.1016/j.tracli.2022.08.145. Epub 2022 Aug 24. [Accessed 25 Jun. 2024] Available at:
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