Tigefen Injection

Introduction

Tigefen is a prescription medication that contains the active ingredient Tigecycline. It is available in the form of an injectable solution. Tigecycline is a broad-spectrum antibiotic that is used to treat various bacterial infections.

Uses

Tigefen is primarily prescribed to treat complicated skin and soft tissue infections caused by certain types of bacteria. It is also used to treat complicated intra-abdominal infections, including appendicitis and infections of the abdominal cavity.

Dosage and Administration

Tigefen should only be administered under the supervision of a healthcare professional. The dosage and duration of treatment will depend on the specific infection being treated, as well as the patient’s age, weight, and overall health.

The injection is usually given intravenously (into a vein) over a period of 30 to 60 minutes. The exact dose and frequency of administration will be determined by the prescribing healthcare professional.

Mechanism of Action

Tigecycline, the active ingredient in Tigefen, belongs to a class of antibiotics called glycylcyclines. It works by inhibiting the synthesis of bacterial proteins, which are essential for the growth and survival of bacteria. This mechanism of action helps to effectively eliminate the bacteria causing the infection.

Side Effects

Common side effects may include nausea, vomiting, diarrhea, headache, and dizziness. These side effects are usually mild and temporary.

However, some serious side effects may occur, although they are rare. These can include severe allergic reactions, liver problems, and a decrease in the number of certain blood cells. If you experience any unusual or severe side effects while using Tigefen, seek medical attention immediately.

Drug Interactions

Tigefen may interact with other medications, including certain antibiotics, anticoagulants, and antacids. Inform your healthcare professional about all the medications you are currently taking, including prescription drugs, over-the-counter medications, and herbal supplements, to avoid any potential drug interactions.

Precautions

Before using Tigefen, inform your healthcare professional if you have any allergies to Tigecycline or any other medications. Additionally, let your healthcare professional know about any medical conditions you have, especially liver or kidney problems.

Tigefen should not be used in children under the age of 8, as it may cause permanent tooth discoloration. It is also not recommended for use during pregnancy or while breastfeeding, as the effects on the unborn baby or nursing infant are not well-established.

Storage

Tigefen should be stored at room temperature, away from direct sunlight and moisture. Keep it out of the reach of children and pets. Do not freeze the medication. If the medication has expired or is no longer needed, dispose of it properly according to local regulations.

Patient Tips

• Follow the dosage instructions provided by your healthcare professional and complete the full course of treatment, even if you start feeling better.
• If you miss a dose, contact your healthcare professional for instructions on how to proceed.
• Drink plenty of fluids while using Tigefen to stay hydrated.
• If you experience severe diarrhea or persistent stomach pain while using this medication, contact your healthcare professional.
• Do not share your medication with others, as it is prescribed specifically for your condition.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Tigecycline (Health Professionals SmPC) Available at:
• Tigecycline (Drugs.com) [Accessed 4 Jun. 2024] (online) Available at:
• tigecycline vial (RX) [Accessed 2 Jun. 2024] (online) Available at:
• Tigecycline Injection (MedlinePlus) [Accessed 8 Jun. 2024] (online) Available at:
• Yaghoubi S, Zekiy AO, Krutova M, Gholami M, Kouhsari E, Sholeh M, Ghafouri Z, Maleki F. Tigecycline antibacterial activity, clinical effectiveness, and mechanisms and epidemiology of resistance: narrative review. Eur J Clin Microbiol Infect Dis. 2022 Jul;41(7):1003-1022. doi: 10.1007/s10096-020-04121-1. Epub 2021 Jan 5. [Accessed 7 Jun. 2024] Available at: