Tilistigmin 15mg Tablet

Introduction

Tilistigmin is a prescription medication that contains the active ingredient Neostigmine. It is available under the brand name Tilistigmin. Neostigmine is a medication that belongs to the class of drugs known as cholinesterase inhibitors. It is primarily used for the treatment of certain conditions that affect muscle strength and coordination.

Uses

Tilistigmin is prescribed for the management of a condition called myasthenia gravis. Myasthenia gravis is an autoimmune disorder that affects the muscles, causing weakness and fatigue. Neostigmine works by increasing the levels of a chemical called acetylcholine in the body, which helps improve muscle strength and coordination.

Dosage and Administration

The dosage of Tilistigmin will vary depending on the individual’s condition and response to treatment. Follow the instructions provided by your healthcare provider. Typically, the initial dose for adults is 15 to 30 milligrams, taken orally every three to four hours. The dosage may be adjusted based on your specific needs. It is important not to exceed the recommended dose without consulting your healthcare provider.

Mechanism of Action

Tilistigmin contains Neostigmine, which works by inhibiting the enzyme acetylcholinesterase. This enzyme is responsible for breaking down acetylcholine, a neurotransmitter that plays a crucial role in muscle function. By inhibiting the breakdown of acetylcholine, Neostigmine helps improve the communication between nerves and muscles, leading to increased muscle strength and coordination.

Side Effects

Common side effects may include nausea, vomiting, abdominal cramps, diarrhea, increased saliva production, sweating, and muscle twitching. These side effects are usually mild and transient. However, if they persist or worsen. Inform your healthcare provider.

Serious side effects of Tilistigmin may include difficulty breathing, severe muscle weakness, chest pain, irregular heartbeat, and seizures. If you experience any of these serious side effects, seek immediate medical attention.

Drug Interactions

Tilistigmin may interact with certain medications, potentially affecting their efficacy or increasing the risk of side effects. Inform your healthcare provider about all the medications you are currently taking, including prescription drugs, over-the-counter medications, and herbal supplements. Common drug interactions may occur with medications such as atropine, anticholinergic drugs, and certain antibiotics. Your healthcare provider will be able to advise you on any necessary precautions or adjustments to your medication regimen.

Precautions

Before taking Tilistigmin, inform your healthcare provider about any existing medical conditions, allergies, or other medications you are taking. This medication may not be suitable for individuals with certain conditions, such as urinary tract obstruction, gastrointestinal obstruction, or asthma. Be cautious if you have a history of heart problems or epilepsy. Your healthcare provider will assess the potential risks and benefits of using Tilistigmin in your specific case.

Storage

Tilistigmin should be stored at room temperature, away from moisture and heat. Keep the medication out of the reach of children and pets. Do not use Tilistigmin if it has expired or if the packaging is damaged.

Patient Tips

• Take Tilistigmin exactly as prescribed by your healthcare provider. Do not adjust the dosage or stop taking the medication without consulting your healthcare provider.
• take each dose with a full glass of water to ensure proper absorption.
• If you miss a dose, take it as soon as you remember. If it is close to the time for your next dose, skip the missed dose and resume your regular dosing schedule.
• Avoid taking other medications or supplements without consulting your healthcare provider, as they may interact with Tilistigmin.
• If you experience any new or worsening symptoms while taking Tilistigmin, inform your healthcare provider promptly.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Glycopyrronium Bromide and Neostigmine Metilsulfate 0.5mg/2.5mg per ml Solution for Injection (Health Professionals SmPC) Available at:
• Neostigmine (Drugs.com) [Accessed 23 Jun. 2024] (online) Available at:
• Intestinal pseudo-obstruction (MedlinePlus) [Accessed 15 Jun. 2024] (online) Available at:
• He W, Chen P, Lei Y, Xia L, Liu P, Zhu Y, Zeng H, Wu Y, Ke H, Huang X, Cai W, Sun X, Huang W, Sutton R, Zhu Y, Lu N. Randomized controlled trial: neostigmine for intra-abdominal hypertension in acute pancreatitis. Crit Care. 2022 Mar 3;26(1):52. doi: 10.1186/s13054-022-03922-4. [Accessed 28 Jun. 2024] Available at: