Tocamide Tablet

Introduction

Tocamide is a prescription medication that contains Acotiamide as its active ingredient. It is available under the brand name Tocamide. This medication is primarily used for the management of certain gastrointestinal disorders.

Uses

Tocamide is prescribed to patients who experience symptoms associated with functional dyspepsia, a condition characterized by recurring indigestion and discomfort in the upper abdomen. It is especially useful for individuals who have difficulty digesting food due to impaired stomach muscle contractions.

Dosage and Administration

The recommended dosage of Tocamide is 100 mg to be taken orally three times a day, preferably before meals. Follow your healthcare professional’s instructions regarding the dosage and duration of treatment. Swallow the tablet whole with a glass of water, and do not crush or chew it.

Mechanism of Action

Acotiamide, the active ingredient in Tocamide, works by enhancing the release of acetylcholine in the gastrointestinal tract. Acetylcholine is a neurotransmitter that plays a crucial role in regulating the movement and function of the digestive system. By increasing the levels of acetylcholine, Tocamide helps to improve the coordination and contraction of stomach muscles, leading to better digestion.

Side Effects

Common side effects include headache, diarrhea, and nausea. These side effects are usually mild and temporary. However, if these symptoms persist or worsen, consult your healthcare provider.

In rare cases, serious side effects may occur. If you experience any of the following, seek immediate medical attention: severe abdominal pain, chest pain, difficulty breathing, or allergic reactions.

Drug Interactions

Tocamide may interact with certain medications, potentially affecting their efficacy or causing adverse effects. Inform your healthcare professional about all the medications you are currently taking, including prescription drugs, over-the-counter medications, and herbal supplements. Some medications that may interact with Tocamide include certain anticholinergic drugs and medications that affect gastric acidity.

Precautions

Before taking Tocamide, inform your healthcare provider about any existing medical conditions or allergies you may have. This medication may not be suitable for individuals with a history of heart rhythm disorders, liver problems, or kidney disease. Avoid consuming alcohol while taking Tocamide, as it may increase the risk of side effects.

Additionally, Tocamide may interact with certain medications, such as anticholinergic drugs or drugs that affect gastric acidity. Your healthcare provider will be able to assess the potential risks and benefits of using Tocamide in combination with other medications.

Storage

Tocamide should be stored at room temperature, away from direct sunlight and moisture. Keep it out of reach of children and pets. Do not use this medication after the expiry date printed on the packaging. If you have any unused or expired tablets, please consult your pharmacist for proper disposal methods.

Patient Tips

• Take the medication as prescribed by your healthcare professional. Do not exceed the recommended dosage or alter the treatment duration without consulting your doctor.
• It is best to take Tocamide before meals, as this can help improve its effectiveness.
• If you experience any severe or persistent side effects, contact your healthcare provider immediately.
• Inform your healthcare provider about all the medications you are taking, including over-the-counter drugs and herbal supplements, to prevent potential drug interactions.
• Follow a healthy diet and lifestyle to support your digestive health. Avoid trigger foods that worsen your symptoms, and maintain a balanced diet.
• If you have any questions or concerns about your treatment with Tocamide, do not hesitate to consult your healthcare provider.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Shrestha DB, Budhathoki P, Subedi P, Khadka M, Karki P, Sedhai YR, Karki BR, Mir WAY. Acotiamide and Functional Dyspepsia: A Systematic Review and Meta-Analysis. Cureus. 2021 Dec 20;13(12):e20532. doi: 10.7759/cureus.20532. eCollection 2021 Dec. [Accessed 29 Jun. 2024] Available at:
• Miwa H, Nagahara A, Asakawa A, Arai M, Oshima T, Kasugai K, Kamada K, Suzuki H, Tanaka F, Tominaga K, Futagami S, Hojo M, Mihara H, Higuchi K, Kusano M, Arisawa T, Kato M, Joh T, Mochida S, Enomoto N, Shimosegawa T, Koike K. Evidence-based clinical practice guidelines for functional dyspepsia 2021. J Gastroenterol. 2022 Feb;57(2):47-61. doi: 10.1007/s00535-021-01843-7. Epub 2022 Jan 21. [Accessed 22 Jun. 2024] Available at:
• Tack J, Janssen P. Acotiamide (Z-338, YM443), a new drug for the treatment of functional dyspepsia. Expert Opin Investig Drugs. 2011 May;20(5):701-12. doi: 10.1517/13543784.2011.562890. Epub 2011 Mar 22. [Accessed 21 Jun. 2024] Available at:
• Ueda M, Iwasaki E, Suzuki H. Profile of acotiamide in the treatment of functional dyspepsia. Clin Exp Gastroenterol. 2016 Apr 6;9:83-8. doi: 10.2147/CEG.S72172. eCollection 2016. [Accessed 16 Jun. 2024] Available at: