Tofe 10mg Tablet

Introduction

Tofe is a prescription medication that contains the active ingredient Tofacitinib. It is available under the brand name Tofe. This medication is primarily used to treat certain autoimmune diseases, including rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis. Tofacitinib works by blocking specific enzymes in the body that contribute to inflammation and joint damage.

Uses

Tofe is prescribed to manage the symptoms and slow the progression of autoimmune diseases such as rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis. It helps reduce joint pain, stiffness, swelling, and inflammation associated with these conditions. Your healthcare provider will determine if Tofe is appropriate for your specific condition.

Dosage and Administration

Tofe should be taken exactly as prescribed by your healthcare professional. The dosage may vary depending on the specific condition being treated and individual factors. It is typically taken orally, with or without food. Swallow the tablet whole with a glass of water, and do not crush, chew, or break it. Follow the instructions provided by your healthcare provider for the most effective and safe use of this medication.

Mechanism of Action

The active ingredient in Tofe, Tofacitinib, belongs to a class of medications known as Janus kinase (JAK) inhibitors. It works by selectively inhibiting specific enzymes called JAKs, which play a role in the immune system response. By blocking these enzymes, Tofacitinib helps reduce inflammation and joint damage associated with autoimmune diseases.

Side Effects

Common side effects may include headache, diarrhea, nausea, and respiratory infections. These side effects are usually mild and temporary. However, if you experience any severe or persistent side effects, such as severe allergic reactions, increased risk of infections, or unusual bleeding or bruising, contact your healthcare provider immediately.

Drug Interactions

inform your healthcare provider about all the medications you are currently taking, including over-the-counter drugs, vitamins, and herbal supplements. Certain medications may interact with Tofe, potentially affecting its effectiveness or increasing the risk of side effects. Common drug interactions may include other immunosuppressive medications, live vaccines, and certain antiviral drugs. Your healthcare provider will provide guidance on any necessary precautions or adjustments to your medication regimen.

Precautions

Before starting Tofe, inform your healthcare provider about any medical conditions you have, especially if you have a history of infections, liver or kidney problems, or certain cancers. This medication may not be suitable for everyone, and your healthcare provider will assess if the benefits outweigh the potential risks. Tofe is not recommended during pregnancy or while breastfeeding.

Storage

Patient Tips

• Take Tofe exactly as prescribed by your healthcare provider.
• Do not stop or change the dosage of this medication without consulting your healthcare provider.
• If you miss a dose, take it as soon as you remember. If it is close to the next scheduled dose, skip the missed dose and continue with your regular dosing schedule.
• Follow any additional instructions provided by your healthcare provider regarding diet, physical activity, and other lifestyle factors that may affect your condition.
• Attend regular follow-up appointments with your healthcare provider to monitor your progress and discuss any concerns or questions you may have.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• XELJANZ 1 mg/mL oral solution (Health Professionals SmPC) Available at:
• Tofacitinib (Drugs.com) [Accessed 30 Jun. 2024] (online) Available at:
• tofacitinib tablet (RX) [Accessed 0 Jun. 2024] (online) Available at:
• Tofacitinib (MedlinePlus) [Accessed 17 Jun. 2024] (online) Available at:
• Sandborn WJ, Su C, Sands BE, D’Haens GR, Vermeire S, Schreiber S, Danese S, Feagan BG, Reinisch W, Niezychowski W, Friedman G, Lawendy N, Yu D, Woodworth D, Mukherjee A, Zhang H, Healey P, Panés J; OCTAVE Induction 1, OCTAVE Induction 2, and OCTAVE Sustain Investigators. Tofacitinib as Induction and Maintenance Therapy for Ulcerative Colitis. N Engl J Med. 2017 May 4;376(18):1723-1736. doi: 10.1056/NEJMoa1606910. [Accessed 8 Jun. 2024] Available at: