Trimetride 2 Tablet PR

Introduction

Trimetride is a prescription medication that combines three active ingredients: Glimepiride, Metformin, and Voglibose. Glimepiride is a sulfonylurea that helps lower blood sugar levels. Metformin is a biguanide that improves insulin sensitivity and reduces glucose production in the liver. Voglibose is an alpha-glucosidase inhibitor that slows down the digestion of carbohydrates, thereby reducing post-meal blood sugar spikes.

Uses

Trimetride is primarily prescribed to manage diabetes mellitus type 2. It is used when diet and exercise alone are not sufficient to control blood sugar levels. This medication helps regulate blood glucose levels and improve glycemic control.

Dosage and Administration

Trimetride should be taken exactly as prescribed by your healthcare provider. The dosage may vary depending on individual needs and response to treatment. It is usually taken once daily with a meal to reduce the risk of gastrointestinal side effects. Swallow the tablet whole with a glass of water. Do not crush or chew the tablet unless advised by your doctor.

Mechanism of Action

The active ingredients in Trimetride work together to help manage diabetes. Glimepiride stimulates the pancreas to produce insulin, which helps lower blood sugar levels. Metformin reduces glucose production in the liver and improves insulin sensitivity in the body’s cells. Voglibose slows down the breakdown of carbohydrates in the intestine, leading to a slower rise in blood glucose levels after meals.

Side Effects

Common side effects may include nausea, diarrhea, stomach upset, and headache. These side effects are usually mild and temporary. However, if you experience any serious side effects such as persistent stomach pain, severe dizziness, or signs of low blood sugar (e.g., sweating, confusion, rapid heartbeat), seek medical attention immediately.

Drug Interactions

inform your healthcare provider about all medications you are taking, including prescription, over-the-counter, and herbal products. Trimetride may interact with certain medications, such as beta-blockers, diuretics, and corticosteroids. These interactions can affect the effectiveness of either medication or increase the risk of side effects. Your healthcare provider will closely monitor your medication regimen to minimize any potential interactions.

Precautions

Before taking Trimetride, inform your healthcare provider about any medical conditions you have, especially liver or kidney problems. This medication may not be suitable for individuals with certain conditions or allergies. Follow your doctor’s instructions and undergo regular blood sugar monitoring while taking this medication. Inform your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding, as this medication may not be recommended during those periods.

Storage

Patient Tips

• Take Trimetride with a meal to reduce the risk of stomach upset.
• Follow a healthy diet and exercise regularly to complement the effects of the medication.
• Keep a record of your blood sugar levels and share them with your healthcare provider during follow-up appointments.
• If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule.
• Always carry a source of fast-acting sugar, such as glucose tablets or candies, in case of low blood sugar episodes.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Glimepiride: medicine to treat type 2 diabetes (NHS UK) [Accessed 4 Jun. 2024] (online) Available at:
• Glimepiride 1 mg tablets (Health Professionals SmPC) Available at:
• Glimepiride (Drugs.com) [Accessed 6 Jun. 2024] (online) Available at:
• glimepiride (amaryl) (RX) [Accessed 9 Jun. 2024] (online) Available at:
• Glimepiride (MedlinePlus) [Accessed 25 Jun. 2024] (online) Available at:
• Ridderstråle M, Andersen KR, Zeller C, Kim G, Woerle HJ, Broedl UC; EMPA-REG H2H-SU trial investigators. Comparison of empagliflozin and glimepiride as add-on to metformin in patients with type 2 diabetes: a 104-week randomised, active-controlled, double-blind, phase 3 trial. Lancet Diabetes Endocrinol. 2014 Sep;2(9):691-700. doi: 10.1016/S2213-8587(14)70120-2. Epub 2014 Jun 16. [Accessed 3 Jun. 2024] Available at: