Triofid 15mg/1mg Tablet

Introduction

Triofid is a prescription medication that contains two active ingredients: Pioglitazone and Glimepiride. It is primarily used to manage blood sugar levels in individuals with type 2 diabetes mellitus. This medication is available in tablet form and is commonly prescribed under the brand name Triofid.

Uses

Triofid is prescribed to help control blood sugar levels in patients with type 2 diabetes mellitus. It is typically used as an adjunct to diet and exercise to improve glycemic control. This medication can be beneficial for individuals who have not achieved adequate blood sugar control with diet and exercise alone.

Dosage and Administration

follow the dosage instructions provided by your healthcare provider. The dosage of Triofid may vary depending on individual factors such as your overall health, response to treatment, and other medications you may be taking. Typically, the initial dose is determined by your healthcare provider and may be adjusted over time.

Triofid is usually taken once daily with a meal. Take this medication exactly as prescribed and not to exceed the recommended dose. Swallow the tablet whole with a glass of water. Do not crush or chew the tablet unless directed by your healthcare provider.

Mechanism of Action

Triofid contains two active ingredients: Pioglitazone and Glimepiride. Pioglitazone is a thiazolidinedione that helps improve insulin sensitivity in the body. It works by increasing the body’s response to insulin, a hormone that helps regulate blood sugar levels. Glimepiride belongs to a class of medications known as sulfonylureas, which stimulate the pancreas to produce more insulin. Together, these two ingredients work to lower blood sugar levels and improve glycemic control in individuals with type 2 diabetes mellitus.

Side Effects

Common side effects may include:

• Weight gain
• Edema (swelling)
• Headache
• Upper respiratory tract infection
• Hypoglycemia (low blood sugar)

note that not everyone will experience these side effects, and some individuals may experience different side effects. If any of these side effects persist or worsen, notify your healthcare provider.

In rare cases, Triofid may cause more serious side effects. These can include:

• Liver problems
• Heart failure
• Bladder cancer (rare)

If you experience any serious side effects or have concerns about potential side effects, seek medical attention immediately.

Drug Interactions

Triofid may interact with other medications, including prescription drugs, over-the-counter medications, and herbal supplements. Inform your healthcare provider about all the medications you are taking, including any supplements or herbal products. Some common drug interactions with Triofid include:

• Insulin or other oral antidiabetic medications: Combined use with Triofid may increase the risk of hypoglycemia.
• Gemfibrozil (a lipid-lowering medication): This medication may increase the concentration of Pioglitazone in the blood, increasing the risk of side effects.
• Rifampicin (an antibiotic): Rifampicin may decrease the concentration of Pioglitazone in the blood, reducing its effectiveness.

This is not an exhaustive list of drug interactions. Always consult your healthcare provider or pharmacist for a complete list of potential drug interactions.

Precautions

Before starting Triofid, discuss any medical conditions or allergies you may have with your healthcare provider. Inform them if you have a history of liver disease, heart problems, bladder cancer, or if you are pregnant or breastfeeding.

Triofid is contraindicated in individuals with a known hypersensitivity to Pioglitazone, Glimepiride, or any other ingredients in the medication.

Monitor your blood sugar levels regularly while taking Triofid. Your healthcare provider may also perform periodic liver function tests and other laboratory tests to monitor your response to the medication.

Storage

Triofid should be stored at room temperature, away from moisture and heat. Keep the medication out of reach of children and pets. Do not use this medication after the expiration date printed on the packaging.

Patient Tips

• Follow your healthcare provider’s instructions: Take the medication exactly as prescribed and do not exceed the recommended dose.
• Monitor your blood sugar levels: Regularly check your blood sugar levels as directed by your healthcare provider.
• Maintain a healthy lifestyle: Continue to follow a balanced diet and engage in regular exercise to support your overall health and help manage your blood sugar levels.
• Stay hydrated: Drink an adequate amount of water throughout the day to stay hydrated.
• Attend regular check-ups: Keep up with your scheduled appointments with your healthcare provider to monitor your progress and adjust your treatment plan if necessary.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Glimepiride: medicine to treat type 2 diabetes (NHS UK) [Accessed 4 Jun. 2024] (online) Available at:
• Glimepiride 1 mg tablets (Health Professionals SmPC) Available at:
• Glimepiride (Drugs.com) [Accessed 6 Jun. 2024] (online) Available at:
• glimepiride (amaryl) (RX) [Accessed 9 Jun. 2024] (online) Available at:
• Glimepiride (MedlinePlus) [Accessed 25 Jun. 2024] (online) Available at:
• Ridderstråle M, Andersen KR, Zeller C, Kim G, Woerle HJ, Broedl UC; EMPA-REG H2H-SU trial investigators. Comparison of empagliflozin and glimepiride as add-on to metformin in patients with type 2 diabetes: a 104-week randomised, active-controlled, double-blind, phase 3 trial. Lancet Diabetes Endocrinol. 2014 Sep;2(9):691-700. doi: 10.1016/S2213-8587(14)70120-2. Epub 2014 Jun 16. [Accessed 3 Jun. 2024] Available at: