Trixalen 25mg Tablet

Introduction

Trixalen is a prescription medication that contains Trioxasalen as its active ingredient. It is available in tablet form and is commonly prescribed by healthcare professionals.

Uses

Trixalen is primarily used for the treatment of a specific skin condition known as vitiligo. Vitiligo is a long-term skin disorder characterized by the loss of skin color in patches. This medication helps to restore the color to the affected areas by increasing the skin’s sensitivity to ultraviolet (UV) light.

Dosage and Administration

follow the dosage instructions provided by your healthcare professional. The dosage of Trixalen may vary depending on the severity of your condition and your individual response to the medication.

Typically, the recommended dose for adults is 10 to 20 mg of Trioxasalen, taken orally, one to two hours before exposure to UVA light. The exact duration and frequency of treatment will be determined by your healthcare professional.

Mechanism of Action

Trixalen works by increasing the skin’s sensitivity to UVA light. Trioxasalen, the active ingredient in this medication, binds to the DNA in skin cells and when activated by UVA light, it helps to restore the color to the depigmented patches of skin in vitiligo.

Side Effects

Common side effects may include:

• Nausea
• Dizziness
• Headache
• Fatigue

If any of these side effects persist or worsen, consult your healthcare professional.

Serious side effects are rare but may include:

• Severe allergic reactions
• Blistering or burning of the skin
• Changes in vision

If you experience any serious side effects, seek immediate medical attention.

Drug Interactions

inform your healthcare professional about all the medications you are currently taking, including prescription, over-the-counter, and herbal products. Some medications may interact with Trixalen and affect its effectiveness or increase the risk of side effects. Common drug interactions may include:

• Psoralen-containing medications
• Photosensitizing agents
• Anticoagulant medications

To minimize the risk of drug interactions, follow your healthcare professional’s advice and inform them about all your current medications.

Precautions

Before using Trixalen, discuss any medical conditions or allergies you may have with your healthcare professional. They will assess whether this medication is suitable for you and determine the appropriate dosage.

Some important precautions to consider include:

• Avoid excessive exposure to sunlight or artificial UV light during treatment.
• Inform your healthcare professional if you are pregnant, planning to become pregnant, or breastfeeding.
• This medication may increase the risk of sunburn, so use appropriate sun protection measures, such as wearing protective clothing and applying sunscreen.
• Inform your healthcare professional if you have a history of skin cancer or any other skin conditions.

Storage

Trixalen should be stored at room temperature, away from moisture and heat. Keep it out of reach of children and pets. Do not use the medication if it has expired.

Patient Tips

• Follow the dosage instructions provided by your healthcare professional and do not exceed the recommended dose.
• Take the medication with food if it upsets your stomach.
• If you miss a dose, take it as soon as you remember. If it is close to the time for your next dose, skip the missed dose and resume your regular dosing schedule.
• Do not stop using Trixalen without consulting your healthcare professional, even if you start to see improvements in your condition.
• If you have any questions or concerns about your treatment, do not hesitate to reach out to your healthcare professional for guidance.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Hadjipavlou-Litina D, E Bariamis S, Militsopoulou M, Athanassopoulos CM, Papaioannou D. Trioxsalen derivatives with lipoxygenase inhibitory activity. J Enzyme Inhib Med Chem. 2009 Dec;24(6):1351-6. doi: 10.3109/14756360902932776. [Accessed 3 Jun. 2024] Available at:
• Skogh M. Trioxsalen vs methoxsalen in the treatment of psoriasis. Arch Dermatol. 1978 Sep;114(9):1399. [Accessed 11 Jun. 2024] Available at:
• Salo OP, Lassus A, Taskinen J. Trioxsalen bath plus UVA treatment of psoriasis. Plasma concentration of the drug and clinical results. Acta Derm Venereol. 1981;61(6):551-4. [Accessed 22 Jun. 2024] Available at:
• Väätäinen N, Hannuksela M, Karvonen J. Trioxsalen baths plus UV-A in the treatment of lichen planus and urticaria pigmentosa. Clin Exp Dermatol. 1981 Mar;6(2):133-8. doi: 10.1111/j.1365-2230.1981.tb02279.x. [Accessed 10 Jun. 2024] Available at: