Trulicity 0.75mg Pre-Filled Pen

Introduction

The Trulicity is a prescription medication that contains the active ingredient Dulaglutide. It is available under the brand name Trulicity. This medication is primarily used for the treatment of type 2 diabetes mellitus in adults.

Uses

Trulicity is prescribed to help control blood sugar levels in adults with type 2 diabetes mellitus. It is used as an adjunct to diet and exercise to improve glycemic control. This medication can be used alone or in combination with other antidiabetic medications, such as metformin or insulin.

Dosage and Administration

The dosage of Trulicity is individualized based on the patient’s response and blood glucose levels. The medication is administered subcutaneously (under the skin) once a week. The pen is pre-filled with the medication and comes with clear instructions on how to use it. Follow the instructions provided by your healthcare provider or pharmacist.

Mechanism of Action

Dulaglutide, the active ingredient in Trulicity, belongs to a class of medications called glucagon-like peptide-1 (GLP-1) receptor agonists. It works by stimulating the release of insulin from the pancreas in response to high blood sugar levels. Additionally, it slows down the absorption of glucose from the intestine and reduces the production of glucose by the liver.

Side Effects

Common side effects may include nausea, vomiting, diarrhea, abdominal pain, and decreased appetite. These side effects are usually mild and temporary.

However, there are some serious side effects that may rarely occur. These can include pancreatitis (inflammation of the pancreas), thyroid tumors, and allergic reactions. If you experience severe abdominal pain, persistent nausea or vomiting, or signs of an allergic reaction (such as rash, itching, or swelling), seek medical attention immediately.

Drug Interactions

Trulicity may interact with certain medications, including insulin or other antidiabetic medications. Inform your healthcare provider about all the medications you are taking, including over-the-counter drugs, vitamins, and herbal supplements. They can help determine if there are any potential interactions and adjust your treatment plan accordingly.

Precautions

Before using Trulicity, inform your healthcare provider about any medical conditions you have, especially if you have a history of pancreatitis, thyroid problems, or kidney disease. This medication may not be suitable for everyone, and your healthcare provider will assess whether it is safe for you to use.

Note that Trulicity should not be used in patients with type 1 diabetes or diabetic ketoacidosis. Additionally, follow the prescribed dosage and not exceed it, as this can increase the risk of side effects.

Storage

Trulicity should be stored in the refrigerator between 36°F to 46°F (2°C to 8°C). Do not freeze the pen. If necessary, the pen can be kept at room temperature, not exceeding 86°F (30°C), for a maximum of 14 days. Once the pen is removed from the refrigerator, it should not be returned.

Patient Tips

• Always follow the instructions provided by your healthcare provider or pharmacist on how to use the Trulicity.
• Keep track of your blood sugar levels regularly and report any significant changes to your healthcare provider.
• If you miss a dose, take it as soon as you remember. If it is close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule.
• Maintain a healthy lifestyle with a balanced diet and regular exercise to help manage your diabetes effectively.
• If you have any concerns or questions about your treatment with Trulicity, do not hesitate to consult your healthcare provider for guidance and support.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• TRULICITY 0.75 mg solution for injection in pre-filled pen (Health Professionals SmPC) Available at:
• Dulaglutide (Drugs.com) [Accessed 15 Jun. 2024] (online) Available at:
• dulaglutide pen injector (RX) [Accessed 17 Jun. 2024] (online) Available at:
• Dulaglutide Injection (MedlinePlus) [Accessed 12 Jun. 2024] (online) Available at:
• Gerstein HC, Colhoun HM, Dagenais GR, Diaz R, Lakshmanan M, Pais P, Probstfield J, Riesmeyer JS, Riddle MC, Rydén L, Xavier D, Atisso CM, Dyal L, Hall S, Rao-Melacini P, Wong G, Avezum A, Basile J, Chung N, Conget I, Cushman WC, Franek E, Hancu N, Hanefeld M, Holt S, Jansky P, Keltai M, Lanas F, Leiter LA, Lopez-Jaramillo P, Cardona Munoz EG, Pirags V, Pogosova N, Raubenheimer PJ, Shaw JE, Sheu WH, Temelkova-Kurktschiev T; REWIND Investigators. Dulaglutide and cardiovascular outcomes in type 2 diabetes (REWIND): a double-blind, randomised placebo-controlled trial. Lancet. 2019 Jul 13;394(10193):121-130. doi: 10.1016/S0140-6736(19)31149-3. Epub 2019 Jun 9. [Accessed 7 Jun. 2024] Available at: