Tussin-DMR Paediatric Syrup

Introduction

Tussin-DMR Paediatric is a prescription medication that contains a combination of active ingredients, including Dextromethorphan Hydrobromide, Cetirizine, Phenylephrine, Ambroxol, Guaifenesin, and Sodium Citrate. It is available under the brand name Tussin-DMR Paediatric. This medication is primarily used to relieve symptoms associated with respiratory conditions, such as cough, congestion, and runny nose.

Uses

Tussin-DMR Paediatric is prescribed for the treatment of respiratory conditions, including coughs, nasal congestion, and excessive mucus production. It provides relief from symptoms commonly associated with respiratory tract infections, allergies, and other respiratory conditions.

Dosage and Administration

The dosage of Tussin-DMR Paediatric may vary depending on the age, weight, and severity of the condition being treated. Follow the instructions provided by your healthcare professional or as mentioned on the product label. Generally, the recommended dosage for adults and children above 12 years of age is 10 ml of syrup every 4 to 6 hours, not exceeding 60 ml in 24 hours.

For children between 6 to 12 years of age, the recommended dosage is 5 ml every 4 to 6 hours, not exceeding 30 ml in 24 hours. Children between 2 to 6 years of age should take 2.5 ml every 4 to 6 hours, not exceeding 15 ml in 24 hours. Use an appropriate measuring device to ensure accurate dosing.

Mechanism of Action

Tussin-DMR Paediatric contains a combination of active ingredients that work together to provide relief from respiratory symptoms.

• Dextromethorphan Hydrobromide acts as a cough suppressant, helping to reduce coughing.
• Cetirizine is an antihistamine that helps relieve symptoms of allergies, such as sneezing and a runny nose.
• Phenylephrine is a decongestant that helps to reduce nasal congestion by constricting blood vessels in the nasal passages.
• Ambroxol is a mucolytic agent that helps to break down and thin mucus, making it easier to cough up.
• Guaifenesin is an expectorant that helps to loosen and expel mucus from the respiratory tract.
• Sodium Citrate acts as an alkalizing agent, helping to reduce the acidity of the respiratory tract and provide soothing relief.

Together, these ingredients work synergistically to alleviate respiratory symptoms and promote easier breathing.

Side Effects

Common side effects may include drowsiness, dizziness, dry mouth, and gastrointestinal disturbances. These side effects are usually mild and temporary.

However, if you experience any of the following serious side effects, seek immediate medical attention:

• Allergic reactions such as rash, itching, swelling, or difficulty breathing
• Severe dizziness or fainting
• Rapid or irregular heartbeat
• Severe stomach pain or vomiting

If you experience any side effects, it is recommended to stop using the medication and consult your healthcare professional.

Drug Interactions

Tussin-DMR Paediatric may interact with other medications, including prescription drugs, over-the-counter medications, and herbal supplements. Inform your healthcare professional about all the medications you are currently taking to avoid potential interactions.

Some common drug interactions include:

• Monoamine oxidase inhibitors (MAOIs) and selective serotonin reuptake inhibitors (SSRIs): Taking Tussin-DMR Paediatric with these medications may increase the risk of serotonin syndrome.
• Sedatives or tranquilizers: Combining Tussin-DMR Paediatric with these medications may increase the sedative effects.
• Blood pressure medications: Phenylephrine, one of the active ingredients in Tussin-DMR Paediatric, may interact with certain blood pressure medications, leading to an increase in blood pressure.

Consult your healthcare professional or pharmacist before starting or stopping any medications while taking Tussin-DMR Paediatric.

Precautions

Before using Tussin-DMR Paediatric, consider the following precautions:

• Contraindications: Do not use Tussin-DMR Paediatric if you are allergic to any of its active ingredients or if you have severe liver or kidney disease.
• Pregnancy and breastfeeding: Consult your healthcare professional before using Tussin-DMR Paediatric if you are pregnant, planning to become pregnant, or breastfeeding.
• Medical conditions: Inform your healthcare professional about any pre-existing medical conditions you have, such as heart disease, high blood pressure, diabetes, or thyroid disorders.

Additionally, avoid alcohol consumption while taking Tussin-DMR Paediatric, as it may increase the risk of drowsiness and other side effects.

Storage

Tussin-DMR Paediatric should be stored at room temperature, away from direct sunlight and moisture. Keep it out of the reach of children and pets. Do not use the medication if it has expired or if the syrup appears discolored or contains particles.

Patient Tips

Here are some helpful tips for patients using Tussin-DMR Paediatric:

• Follow the dosage instructions provided by your healthcare professional or as mentioned on the product label.
• Use an appropriate measuring device to ensure accurate dosing.
• If you forget to take a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule.
• Avoid driving or operating heavy machinery if you experience drowsiness or dizziness while taking Tussin-DMR Paediatric.
• Stay hydrated by drinking plenty of fluids while using this medication to help thin mucus and promote easier expectoration.
• If your symptoms worsen or persist despite using Tussin-DMR Paediatric, consult your healthcare professional.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Cetirizine: antihistamine that relieves allergy symptoms (NHS UK) [Accessed 22 Jun. 2024] (online) Available at:
• allacan 10mg film-coated tablets (Health Professionals SmPC) Available at:
• Ambroxol (Drugs.com) [Accessed 30 Jun. 2024] (online) Available at:
• all day allergy relief (cetirizine) 10 mg tablet (OTC) [Accessed 20 Jun. 2024] (online) Available at:
• Cetirizine (MedlinePlus) [Accessed 6 Jun. 2024] (online) Available at:
• Malerba M, Ragnoli B. Ambroxol in the 21st century: pharmacological and clinical update. Expert Opin Drug Metab Toxicol. 2008 Aug;4(8):1119-29. doi: 10.1517/17425255.4.8.1119. [Accessed 27 Jun. 2024] Available at: