Introduction
Unigrilin is the brand name for a medication with the generic name Eptifibatide. It is primarily used in the treatment and prevention of blood clots in patients with certain heart or blood vessel conditions.
Uses
Unigrilin is prescribed for patients who have acute coronary syndrome, including those undergoing percutaneous coronary intervention (PCI) such as angioplasty or stent placement. It helps prevent blood clots from forming during and after these procedures, reducing the risk of heart attack or stroke.
Dosage and Administration
The dosage and administration of Unigrilin are determined by a healthcare professional based on the patient’s specific condition and medical history. It is typically administered intravenously and the dosage regimen may vary, but follow the healthcare provider’s instructions carefully.
Mechanism of Action
Eptifibatide, the active ingredient in Unigrilin, works by preventing blood platelets from clumping together and forming blood clots. This helps maintain blood flow through the coronary arteries and reduces the risk of blockages that can lead to serious cardiovascular events.
Side Effects
Common side effects of Unigrilin may include bleeding from the injection site, nosebleeds, or easy bruising. Serious side effects may include severe bleeding, such as blood in the urine or stools, or unusual weakness. Patients should seek immediate medical attention if they experience any serious side effects.
Drug Interactions
Unigrilin may interact with other medications that affect blood clotting, such as anticoagulants or antiplatelet drugs. It is important for patients to inform their healthcare provider about all medications, supplements, and herbal products they are taking to avoid potential interactions.
Precautions
Patients receiving Unigrilin should be cautious when undergoing procedures with a risk of bleeding, such as surgery, and inform their healthcare providers about their medication use. Avoid using non-prescription medications that can increase the risk of bleeding while taking Unigrilin.
Storage
Unigrilin should be stored at the recommended temperature as specified by the manufacturer. Keep the medication out of reach of children and away from direct sunlight or moisture.
Patient Tips
Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.
References
- INTEGRILIN 0.75 mg/ml solution for infusion (Health Professionals SmPC) Available at:
- Eptifibatide (Drugs.com) [Accessed 26 Jun. 2024] (online) Available at:
- LactMed: Drugs and Lactation Database (National Library of Medicine) [Accessed 5 Jun. 2024] (online) Available at:
- Parakh S, Naik N, Rohatgi N, Bhat U, Parakh K. Eptifibatide overdose. Int J Cardiol. 2009 Jan 24;131(3):430-2. doi: 10.1016/j.ijcard.2007.07.132. Epub 2007 Nov 19. [Accessed 3 Jun. 2024] Available at:
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