Vinem-S 1500 Injection

Introduction

Vinem-S is a medication that contains the active ingredients Meropenem and Sulbactam. It is available in the form of an injection and is used for the treatment of certain bacterial infections.

Uses

Vinem-S is prescribed for the treatment of various infections caused by susceptible bacteria. It is commonly used for the treatment of:

• Intra-abdominal infections
• Skin and soft tissue infections
• Urinary tract infections
• Lower respiratory tract infections

note that Vinem-S should only be used for bacterial infections and not for viral infections such as the common cold or flu.

Dosage and Administration

The dosage of Vinem-S will vary depending on the specific infection being treated, the severity of the infection, and the patient’s individual factors such as age and weight. Follow the dosage instructions provided by your healthcare professional.

Vinem-S is administered by a healthcare professional through intravenous (IV) infusion. The injection is typically given over a period of 30 minutes to 1 hour. The exact administration method and duration will be determined by your healthcare professional.

Mechanism of Action

Vinem-S contains two active ingredients: Meropenem and Sulbactam.

• Meropenem belongs to the class of antibiotics known as carbapenems. It works by inhibiting the growth of bacteria and interfering with the synthesis of their cell walls, ultimately leading to bacterial cell death.
• Sulbactam is a beta-lactamase inhibitor. It works by inhibiting the enzymes produced by bacteria that can inactivate certain antibiotics, such as penicillins and cephalosporins. By inhibiting these enzymes, Sulbactam helps to enhance the effectiveness of Meropenem against bacteria.

The combination of Meropenem and Sulbactam in Vinem-S provides a broad spectrum of activity against various bacteria.

Side Effects

Common side effects may include:

• Nausea
• Vomiting
• Diarrhea
• Headache
• Rash

note that not all patients will experience these side effects, and some individuals may experience different or more severe side effects. If you experience any unusual or persistent side effects while using Vinem-S, contact your healthcare professional.

In rare cases, Vinem-S may cause serious side effects such as allergic reactions or severe skin reactions. If you experience symptoms such as difficulty breathing, swelling of the face or throat, or a severe skin rash, seek immediate medical attention.

Drug Interactions

Vinem-S may interact with other medications, including prescription drugs, over-the-counter medications, and herbal supplements. Inform your healthcare professional about all the medications and supplements you are currently taking to avoid potential drug interactions.

Some medications that may interact with Vinem-S include:

• Probenecid: May increase the blood levels of Meropenem, potentially leading to an increased risk of side effects.
• Valproic acid: Concurrent use with Meropenem may decrease the blood levels of valproic acid, potentially reducing its effectiveness.

This is not an exhaustive list of drug interactions. Always consult with your healthcare professional for a complete list of medications that may interact with Vinem-S.

Precautions

Before using Vinem-S, inform your healthcare professional about any allergies you may have, as well as your medical history, including any previous adverse reactions to antibiotics.

• Contraindications: Vinem-S is contraindicated in individuals with a known hypersensitivity to Meropenem, Sulbactam, or any other component of the medication.
• Pregnancy and breastfeeding: Vinem-S should be used with caution during pregnancy and breastfeeding. Discuss the potential risks and benefits with your healthcare professional.
• Renal impairment: Vinem-S may require dosage adjustments in individuals with impaired kidney function. Your healthcare professional will determine the appropriate dosage based on your renal function.

Storage

Patient Tips

• Follow the dosage instructions provided by your healthcare professional and complete the full course of treatment, even if you start to feel better.
• If you miss a dose, contact your healthcare professional for guidance on how to proceed.
• Inform your healthcare professional about any other medications or supplements you are taking to avoid potential drug interactions.
• If you experience any unusual or persistent side effects, contact your healthcare professional.
• Store the medication properly as directed by the manufacturer.
• Do not use Vinem-S for viral infections such as the common cold or flu.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Meronem IV 1g Powder for solution for injection or infusion (Health Professionals SmPC) Available at:
• Meropenem (Drugs.com) [Accessed 22 Jun. 2024] (online) Available at:
• meropenem vial (RX) [Accessed 29 Jun. 2024] (online) Available at:
• Meropenem and Vaborbactam Injection (MedlinePlus) [Accessed 23 Jun. 2024] (online) Available at:
• Pascale R, Giannella M, Bartoletti M, Viale P, Pea F. Use of meropenem in treating carbapenem-resistant Enterobacteriaceae infections. Expert Rev Anti Infect Ther. 2019 Oct;17(10):819-827. doi: 10.1080/14787210.2019.1673731. Epub 2019 Oct 8. [Accessed 0 Jun. 2024] Available at: