Vitree Solution

Introduction

Vitree is a prescription medication that contains the active ingredient Trioxasalen. It is available under the brand name Vitree. This medication is primarily used in the treatment of certain skin conditions, specifically vitiligo and psoriasis.

Uses

Vitree is prescribed for the treatment of vitiligo and psoriasis. Vitiligo is a condition characterized by the loss of skin color in patches, while psoriasis is a chronic skin disorder that leads to the development of red, scaly patches on the skin.

Dosage and Administration

The dosage of Vitree should be determined by your healthcare provider based on your specific condition and medical history. Follow the instructions provided by your healthcare provider or the directions on the prescription label.

Vitree is typically applied topically to the affected areas of the skin. The exact method of administration will depend on the specific instructions provided by your healthcare provider. Apply the solution only to the areas of the skin that require treatment and to avoid contact with unaffected areas.

Mechanism of Action

The active ingredient in Vitree, Trioxasalen, works by sensitizing the skin to ultraviolet (UV) light. When applied to the skin and exposed to UVA or sunlight, Trioxasalen binds to the DNA in the skin cells. This binding process helps to restore skin color in vitiligo and reduce the inflammation and scaling associated with psoriasis.

Side Effects

Common side effects may include skin redness, dryness, itching, or a mild burning sensation at the application site. These side effects are usually mild and temporary.

However, some individuals may experience more serious side effects. If you notice any severe skin reactions, such as blistering, severe redness, or swelling, seek medical attention immediately.

Drug Interactions

Vitree may interact with certain medications. Inform your healthcare provider about all the medications you are currently taking, including prescription, over-the-counter, and herbal products. Some medications, such as certain antibiotics and antidepressants, may increase the sensitivity of the skin to UV light, which can potentially increase the risk of side effects.

Precautions

Before using Vitree, inform your healthcare provider about any existing medical conditions or allergies you may have. This medication may not be suitable for individuals with a history of skin cancer, certain blood disorders, or liver problems.

Avoid excessive sun exposure or the use of tanning beds while using Vitree, as this can increase the risk of skin damage. Additionally, avoid contact with the eyes, mouth, or open wounds when applying the solution.

Storage

Vitree should be stored at room temperature, away from direct sunlight and moisture. Keep the bottle tightly closed when not in use. Do not freeze the solution. Keep this medication out of reach of children and pets.

Patient Tips

• Follow the dosage instructions provided by your healthcare provider or as indicated on the prescription label.
• Apply Vitree only to the affected areas of the skin as directed by your healthcare provider.
• Avoid excessive sun exposure and protect your skin with sunscreen and protective clothing while using this medication.
• If you experience any severe skin reactions or side effects, contact your healthcare provider immediately.
• Inform your healthcare provider about all the medications you are taking to avoid potential drug interactions.
• Store Vitree in a cool, dry place and keep it out of reach of children and pets.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Hadjipavlou-Litina D, E Bariamis S, Militsopoulou M, Athanassopoulos CM, Papaioannou D. Trioxsalen derivatives with lipoxygenase inhibitory activity. J Enzyme Inhib Med Chem. 2009 Dec;24(6):1351-6. doi: 10.3109/14756360902932776. [Accessed 3 Jun. 2024] Available at:
• Sánchez Ruderisch H, Schwarz C, Shang J, Tebbe B. Trioxsalen in the presence of UVA is able to induce nuclear factor kappa B binding activity in HaCaT keratinocytes. Skin Pharmacol Appl Skin Physiol. 2002 Sep-Oct;15(5):335-41. doi: 10.1159/000064538. [Accessed 2 Jun. 2024] Available at:
• Hannuksela-Svahn A, Sigurgeirsson B, Pukkala E, Lindelöf B, Berne B, Hannuksela M, Poikolainen K, Karvonen J. Trioxsalen bath PUVA did not increase the risk of squamous cell skin carcinoma and cutaneous malignant melanoma in a joint analysis of 944 Swedish and Finnish patients with psoriasis. Br J Dermatol. 1999 Sep;141(3):497-501. doi: 10.1046/j.1365-2133.1999.03044.x. [Accessed 11 Jun. 2024] Available at:
• Skogh M. Trioxsalen vs methoxsalen in the treatment of psoriasis. Arch Dermatol. 1978 Sep;114(9):1399. [Accessed 11 Jun. 2024] Available at: