Votrient 400mg Tablet

Introduction

Votrient is a prescription medication that contains the active ingredient Pazopanib. It is available under the brand name Votrient. This medication is primarily used in the treatment of certain types of advanced kidney cancer and soft tissue sarcoma. It belongs to a class of medications called tyrosine kinase inhibitors, which work by blocking specific proteins in the body that promote the growth of cancer cells.

Uses

Votrient is prescribed for the following conditions:

• Advanced kidney cancer: It is used to treat adults with advanced kidney cancer that has spread to other parts of the body.
• Soft tissue sarcoma: It is used to treat adults with certain types of soft tissue sarcoma that cannot be treated with surgery alone.

Dosage and Administration

• The recommended dosage of Votrient may vary depending on the individual’s condition and response to treatment. Follow the instructions provided by your healthcare professional.
• The tablets should be taken orally, preferably with a meal and a full glass of water.
• Do not crush, chew, or break the tablets. Swallow them whole.

Mechanism of Action

Pazopanib, the active ingredient in Votrient, works by inhibiting the activity of certain proteins in the body that are involved in the growth of cancer cells. It specifically targets and blocks the activity of tyrosine kinases, which are involved in signaling pathways that promote cell growth and division. By inhibiting these proteins, Votrient helps slow down the growth and spread of cancer cells.

Side Effects

Common side effects may include:

• Fatigue
• Diarrhea
• Nausea
• Loss of appetite
• High blood pressure

note that not all individuals will experience these side effects, and some may experience different or more severe side effects. If you experience any severe or persistent side effects. Consult your healthcare professional immediately.

Drug Interactions

Votrient may interact with other medications, including both prescription and over-the-counter drugs, as well as herbal supplements. Inform your healthcare professional about all the medications and supplements you are taking before starting treatment with Votrient. Some common drug interactions may include:

• Anticoagulants (blood thinners)
• Anticonvulsants
• Certain antibiotics
• Antifungal medications
• Certain heart medications

This is not an exhaustive list, and there may be other drug interactions. Consult your healthcare professional or pharmacist for a complete list of potential drug interactions.

Precautions

Before taking Votrient, take note of the following precautions:

• Allergies: Inform your healthcare professional if you have any known allergies to Pazopanib or any other medications.
• Pregnancy and breastfeeding: Votrient may cause harm to an unborn baby, so discuss the risks and benefits with your healthcare professional if you are pregnant or planning to become pregnant. It is also not recommended to breastfeed while taking this medication.
• Other medical conditions: Inform your healthcare professional about any other medical conditions you have, including liver or kidney problems, heart disease, high blood pressure, or bleeding disorders.

Storage

Patient Tips

• Follow your healthcare professional’s instructions regarding the dosage and administration of Votrient.
• Take the tablets with a meal and a full glass of water to help reduce the risk of stomach upset.
• If you miss a dose, take it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and resume your regular dosing schedule.
• Do not stop taking Votrient without consulting your healthcare professional, even if you start to feel better.
• attend all scheduled appointments with your healthcare professional for regular monitoring and evaluation of your condition.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Votrient 200 mg film coated tablets (Health Professionals SmPC) Available at:
• Pazopanib (Drugs.com) [Accessed 24 Jun. 2024] (online) Available at:
• pazopanib 200 mg tablet antineoplastic – protein-tyrosine kinase inhibitors (RX) [Accessed 25 Jun. 2024] (online) Available at:
• Pazopanib (MedlinePlus) [Accessed 26 Jun. 2024] (online) Available at:
• van der Graaf WT, Blay JY, Chawla SP, Kim DW, Bui-Nguyen B, Casali PG, Schöffski P, Aglietta M, Staddon AP, Beppu Y, Le Cesne A, Gelderblom H, Judson IR, Araki N, Ouali M, Marreaud S, Hodge R, Dewji MR, Coens C, Demetri GD, Fletcher CD, Dei Tos AP, Hohenberger P; EORTC Soft Tissue and Bone Sarcoma Group; PALETTE study group. Pazopanib for metastatic soft-tissue sarcoma (PALETTE): a randomised, double-blind, placebo-controlled phase 3 trial. Lancet. 2012 May 19;379(9829):1879-86. doi: 10.1016/S0140-6736(12)60651-5. Epub 2012 May 16. [Accessed 18 Jun. 2024] Available at: