Zalkuff DMR 5mg/2mg/10mg Tablet

Introduction

Zalkuff DMR is a prescription medication that combines three active ingredients: Phenylephrine, Chlorpheniramine Maleate, and Dextromethorphan Hydrobromide. It is available in tablet form and is commonly known by its brand name Zalkuff DMR. This medication is primarily used to relieve symptoms associated with common colds and allergies, such as nasal congestion, runny nose, sneezing, and coughing.

Uses

Zalkuff DMR is prescribed for the temporary relief of symptoms caused by the common cold, hay fever, and other respiratory allergies. It can help alleviate nasal congestion, reduce sneezing, relieve runny nose, and suppress coughing.

Dosage and Administration

The dosage and administration of Zalkuff DMR may vary depending on the individual and the specific condition being treated. Follow the instructions provided by your healthcare professional or as indicated on the packaging. Generally, the recommended dose for adults and children over 12 years of age is one tablet every 4 to 6 hours, as needed. However, consult with your doctor or pharmacist for personalized dosing instructions.

Mechanism of Action

Phenylephrine, one of the active ingredients in Zalkuff DMR, is a nasal decongestant that works by narrowing the blood vessels in the nasal passages, reducing congestion and allowing for easier breathing. Chlorpheniramine Maleate is an antihistamine that blocks the effects of histamine, a substance produced by the body during an allergic reaction. This helps relieve symptoms such as sneezing and runny nose. Dextromethorphan Hydrobromide is a cough suppressant that acts on the cough center in the brain, reducing the urge to cough.

Side Effects

Common side effects may include drowsiness, dizziness, dry mouth, and blurred vision. These side effects are usually mild and temporary. However, if you experience any severe or persistent side effects, such as rapid heartbeat, difficulty urinating, hallucinations, or allergic reactions, seek medical attention immediately.

Drug Interactions

Zalkuff DMR may interact with certain medications, including monoamine oxidase inhibitors (MAOIs), selective serotonin reuptake inhibitors (SSRIs), and other medications that can cause drowsiness or central nervous system depression. Inform your healthcare professional about all the medications you are currently taking, including prescription, over-the-counter, and herbal products, to avoid potential drug interactions.

Precautions

Before taking Zalkuff DMR, inform your healthcare professional about any known allergies, medical conditions, or other medications you are taking. This medication may not be suitable for individuals with certain conditions, such as high blood pressure, heart disease, diabetes, thyroid problems, or prostate enlargement. Avoid consuming alcohol or operating machinery while taking this medication, as it may cause drowsiness.

Storage

Patient Tips

• Follow the dosage instructions provided by your healthcare professional or as indicated on the packaging.
• If you are unsure about any aspect of the medication, consult your doctor or pharmacist for clarification.
• Avoid taking other medications that contain the same or similar active ingredients to prevent accidental overdose.
• Stay hydrated by drinking plenty of fluids while taking Zalkuff DMR.
• If symptoms persist or worsen after a few days of treatment, consult your healthcare professional for further evaluation.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Chlorphenamine: drowsy (sedating) antihistamine (NHS UK) [Accessed 29 Jun. 2024] (online) Available at:
• Benylin Dry Coughs (Original) (Health Professionals SmPC) Available at:
• Chlorpheniramine (Drugs.com) [Accessed 27 Jun. 2024] (online) Available at:
• chlorpheniramine maleate (OTC) [Accessed 11 Jun. 2024] (online) Available at:
• Codeine (MedlinePlus) [Accessed 21 Jun. 2024] (online) Available at:
• Kumar M, Upadhayay P, Shankar R, Joshi M, Bhatt S, Malik A. Chlorpheniramine maleate containing chitosan-based nanoparticle-loaded thermosensitive in situ gel for management in allergic rhinitis. Drug Deliv Transl Res. 2019 Dec;9(6):1017-1026. doi: 10.1007/s13346-019-00639-w. [Accessed 13 Jun. 2024] Available at: