Zerofos DS Tablet

Introduction

Zerofos DS is a prescription medication that contains Calcium Acetate as its active ingredient. It is commonly available under the brand name Zerofos DS. This medication is primarily used for the treatment of hyperphosphatemia in patients with chronic kidney disease (CKD).

Uses

Zerofos DS is prescribed to patients with CKD to help lower and control high levels of phosphate in the blood. Excess phosphate in the body can lead to complications such as bone disease, heart problems, and calcification of soft tissues. By reducing the absorption of phosphate from food, Zerofos DS helps maintain the proper balance of minerals in the body.

Dosage and Administration

The dosage of Zerofos DS will vary depending on the individual and their specific medical condition. Follow the instructions provided by your healthcare professional. Typically, the recommended starting dose for adults is 2 tablets taken three times a day with meals. The dosage may be adjusted based on your response to the medication and your phosphate levels.

Zerofos DS should be taken orally with water, preferably with meals or as directed by your doctor. Swallow the tablet whole and not crush or chew it. If you have difficulty swallowing the tablet, speak to your healthcare provider for alternative options.

Mechanism of Action

Calcium Acetate, the active ingredient in Zerofos DS, works by binding to dietary phosphate in the gastrointestinal tract. This prevents its absorption into the bloodstream, reducing the overall phosphate levels in the body. By controlling phosphate levels, Zerofos DS helps prevent complications associated with hyperphosphatemia.

Side Effects

Common side effects include nausea, vomiting, constipation, diarrhea, and abdominal pain. These side effects are usually mild and may improve over time. If any of these side effects persist or worsen, inform your healthcare provider.

Serious side effects are rare but can occur. If you experience any of the following, seek immediate medical attention: severe stomach pain, loss of appetite, confusion, irregular heartbeat, muscle weakness, or signs of an allergic reaction (rash, itching, swelling, severe dizziness, difficulty breathing).

Drug Interactions

inform your healthcare provider about all the medications you are taking, including prescription, over-the-counter, and herbal products. Some medications may interact with Zerofos DS and affect its effectiveness or increase the risk of side effects. Common drug interactions include antacids containing aluminum, magnesium, or calcium, certain antibiotics, and certain heart medications. Your healthcare provider will closely monitor your medication regimen to ensure its safety and efficacy.

Precautions

Before starting Zerofos DS, discuss any pre-existing medical conditions or allergies with your healthcare provider. Certain conditions, such as hypercalcemia (high calcium levels) or hypoparathyroidism (underactive parathyroid glands), may require special consideration or dosage adjustments.

Avoid taking any other calcium supplements while using Zerofos DS, as this may lead to excessive calcium levels in the body. Additionally, Zerofos DS may interact with certain medications, so it is vital to inform your healthcare provider about all the medications you are taking.

Storage

Zerofos DS should be stored at room temperature, away from excessive heat, moisture, and direct sunlight. Keep the medication out of reach of children and pets. Do not use Zerofos DS if the tablets are expired or if the packaging is damaged.

Patient Tips

• Take Zerofos DS with meals or as directed by your healthcare professional to improve its absorption and reduce the risk of gastrointestinal side effects.
• Follow a well-balanced diet and avoid foods high in phosphate, such as dairy products, nuts, and certain processed foods, as this can help optimize the effects of Zerofos DS.
• If you miss a dose, take it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose to make up for a missed one.
• Stay hydrated by drinking an adequate amount of fluids, unless otherwise advised by your healthcare provider. This can help support kidney function and optimize the effects of Zerofos DS.
• Attend regular follow-up appointments with your healthcare provider to monitor your progress, adjust the dosage if needed, and evaluate any potential side effects.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Vitamins and minerals – Calcium (NHS UK) [Accessed 28 Jun. 2024] (online) Available at:
• CLINIMIX N14G30E, solution for infusion (Health Professionals SmPC) Available at:
• Calcium acetate (Drugs.com) [Accessed 6 Jun. 2024] (online) Available at:
• calcium acetate (RX) [Accessed 23 Jun. 2024] (online) Available at:
• Calcium Acetate (MedlinePlus) [Accessed 0 Jun. 2024] (online) Available at:
• Wang Y, Xie G, Huang Y, Zhang H, Yang B, Mao Z. Calcium acetate or calcium carbonate for hyperphosphatemia of hemodialysis patients: a meta-analysis. PLoS One. 2015 Mar 23;10(3):e0121376. doi: 10.1371/journal.pone.0121376. eCollection 2015. [Accessed 29 Jun. 2024] Available at: