Zolingerd D 30mg/40mg Tablet SR

Introduction

Zolingerd D is a prescription medication that contains two active ingredients: Domperidone and Pantoprazole. Domperidone is a medication that helps to improve gastric motility and reduce nausea and vomiting. Pantoprazole belongs to a class of medications called proton pump inhibitors, which help to reduce the production of stomach acid. Zolingerd D is primarily used in the treatment of gastrointestinal disorders such as gastroesophageal reflux disease (GERD), peptic ulcers, and dyspepsia.

Uses

Zolingerd D is prescribed to manage symptoms associated with various gastrointestinal conditions, including:

• Gastroesophageal reflux disease (GERD): This condition causes acid from the stomach to flow back into the esophagus, resulting in heartburn, chest pain, and regurgitation.
• Peptic ulcers: Zolingerd D can help in the healing and prevention of ulcers in the stomach and duodenum (the first part of the small intestine).
• Dyspepsia: Also known as indigestion, dyspepsia causes pain and discomfort in the upper abdomen, bloating, and a feeling of fullness after eating.

It’s important to note that Zolingerd D should only be used under the guidance of a healthcare professional.

Dosage and Administration

• The dosage of Zolingerd D may vary depending on the individual’s condition, age, and medical history. Follow the specific instructions provided by your healthcare professional.
• The tablets should be swallowed whole with a glass of water and should not be crushed or chewed.
• Zolingerd D is usually taken before meals to maximize its effectiveness in reducing stomach acid production.

Mechanism of Action

Zolingerd D works through its active ingredients, Domperidone and Pantoprazole, to provide relief from gastrointestinal symptoms.

• Domperidone helps to improve gastric motility by blocking the action of dopamine in the gut. This helps to reduce nausea, vomiting, and other symptoms associated with gastrointestinal disorders.
• Pantoprazole works by inhibiting the proton pumps in the stomach, which are responsible for the production of stomach acid. By reducing acid production, it helps to relieve symptoms such as heartburn and acid reflux.

Side Effects

be aware of the possible side effects and seek medical attention if they occur. Common side effects may include:

• Headache
• Dizziness
• Diarrhea
• Abdominal pain
• Nausea

Serious side effects are rare but may include:

• Allergic reactions such as rash, itching, or swelling of the face, lips, tongue, or throat
• Irregular heartbeat
• Severe stomach pain
• Yellowing of the skin or eyes (jaundice)

If you experience any of these serious side effects, seek immediate medical attention.

Drug Interactions

Zolingerd D may interact with other medications, potentially affecting their effectiveness or increasing the risk of side effects. Inform your healthcare professional about all the medications you are currently taking, including prescription, over-the-counter, and herbal products. Common drug interactions may include:

• Ketoconazole
• Digoxin
• Warfarin
• Methotrexate

This is not an exhaustive list, and there may be other medications that can interact with Zolingerd D. Always consult your healthcare professional for personalized advice.

Precautions

Before starting Zolingerd D, consider the following precautions:

• Inform your healthcare professional about any known allergies or sensitivities to Domperidone, Pantoprazole, or any other medications.
• Discuss your medical history, including any liver or kidney problems, with your healthcare professional.
• Zolingerd D may not be suitable for use during pregnancy or breastfeeding. Consult your healthcare professional for guidance.
• Avoid consuming alcohol while taking Zolingerd D, as it may increase the risk of side effects.
• Be cautious when driving or operating machinery, as Zolingerd D may cause dizziness or drowsiness.

Storage

To ensure the stability and effectiveness of Zolingerd D, store it properly:

• Keep the tablets in their original packaging, away from moisture and direct sunlight.
• Store at a temperature below 25°C (77°F).
• Do not refrigerate or freeze the tablets.
• Keep Zolingerd D out of the reach of children and pets.

Patient Tips

Here are a few additional tips to keep in mind while using Zolingerd D:

• Take the medication exactly as prescribed by your healthcare professional. Do not change the dosage or stop taking the medication without consulting them first.
• If you miss a dose, take it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule.
• It may take some time for Zolingerd D to provide relief from your symptoms. If you do not experience improvement or if your symptoms worsen, consult your healthcare professional.
• If you have any questions or concerns about Zolingerd D, don’t hesitate to reach out to your healthcare professional for clarification.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Domperidone: anti-sickness medicine for nausea and vomiting (NHS UK) [Accessed 10 Jun. 2024] (online) Available at:
• Domperidone 10 mg film-coated tablets (Health Professionals SmPC) Available at:
• Domperidone (Drugs.com) [Accessed 4 Jun. 2024] (online) Available at:
• pantoprazole sodium (RX) [Accessed 11 Jun. 2024] (online) Available at:
• Definitions of Digestive Terms (International Foundation for Gastrointestinal Disorders) [Accessed 3 Jun. 2024] (online) Available at:
• Puoti MG, Assa A, Benninga M, Broekaert IJ, Carpi FJM, Deganello Saccomani M, Dolinsek J, Homan M, Mas E, Miele E, Tzivinikos C, Thomson M, Borrelli O. Drugs in Focus: Domperidone. J Pediatr Gastroenterol Nutr. 2023 Aug 1;77(2):e13-e22. doi: 10.1097/MPG.0000000000003822. Epub 2023 May 9. [Accessed 7 Jun. 2024] Available at: