Introduction
Zomelis SG is a prescription medication that contains two active ingredients: Remogliflozin Etabonate and Vildagliptin. It is used to manage type 2 diabetes mellitus in adults.
Uses
Zomelis SG is primarily prescribed to lower blood sugar levels in patients with type 2 diabetes mellitus. It helps improve glycemic control by reducing the amount of glucose absorbed by the kidneys and increasing insulin production in the pancreas.
Dosage and Administration
The dosage of Zomelis SG may vary depending on individual patient characteristics and the severity of their condition. Follow the instructions provided by your healthcare provider. Typically, the recommended starting dose is one tablet taken orally once a day, preferably before a meal. Your doctor may adjust the dose as needed to achieve optimal blood sugar control. Do not exceed the prescribed dose without consulting your doctor.
Mechanism of Action
Remogliflozin Etabonate, one of the active ingredients in Zomelis SG, works by inhibiting the sodium-glucose cotransporter 2 (SGLT2) in the kidneys. This reduces the reabsorption of glucose, leading to increased glucose excretion in the urine and lower blood sugar levels. Vildagliptin, the other active ingredient, belongs to a class of medications called dipeptidyl peptidase-4 (DPP-4) inhibitors. It works by increasing the levels of incretin hormones, which stimulate insulin secretion and reduce glucagon release, thereby improving glycemic control.
Side Effects
Common side effects may include urinary tract infections, upper respiratory tract infections, headache, dizziness, and gastrointestinal symptoms such as nausea and diarrhea. Serious side effects are rare but may include hypoglycemia (low blood sugar), pancreatitis, and hypersensitivity reactions. If you experience any of these serious side effects or any other unexpected symptoms, seek medical attention immediately.
Drug Interactions
Zomelis SG may interact with certain medications, which can affect its efficacy or increase the risk of side effects. Inform your healthcare provider about all the medications you are currently taking, including prescription, over-the-counter, and herbal products. Of particular importance are medications that lower blood sugar levels, such as insulin or other oral antidiabetic drugs. Your doctor will monitor your blood sugar levels closely and adjust your medication regimen if necessary.
Precautions
Before starting Zomelis SG, inform your healthcare provider about any existing medical conditions, including kidney or liver problems. This medication is not recommended for use in patients with severe renal impairment or end-stage renal disease. Disclose any allergies or sensitivities to medications. Zomelis SG is contraindicated during pregnancy and breastfeeding. Discuss alternative treatment options with your doctor if you are pregnant or planning to become pregnant.
Storage
Patient Tips
- Take Zomelis SG exactly as prescribed by your healthcare provider. Do not skip doses or stop taking the medication without consulting your doctor.
- Follow a healthy diet and exercise regimen as recommended by your doctor to complement the effects of Zomelis SG.
- Monitor your blood sugar levels regularly and report any significant changes to your healthcare provider.
- Stay hydrated and drink plenty of water to help prevent urinary tract infections.
- Carry a form of identification or wear a medical alert bracelet indicating that you are taking Zomelis SG in case of emergencies.
- Attend regular follow-up appointments with your doctor to assess the effectiveness of the medication and make any necessary adjustments to your treatment plan.
Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.
References
- Eucreas 50 mg/1000 mg film-coated tablets (Health Professionals SmPC) Available at:
- Lotemax: Uses, Directions, Side Effects, Warnings Consumer Information (Drugs.com) [Accessed 18 Jun. 2024] (online) Available at:
- Markham A. Remogliflozin Etabonate: First Global Approval. Drugs. 2019 Jul;79(10):1157-1161. doi: 10.1007/s40265-019-01150-9. [Accessed 24 Jun. 2024] Available at:
- Vildagliptin/Metformin 50 mg/1000 mg Film-coated Tablets (Health Professionals SmPC) Available at:
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