Zoryl-M 2 Tablet PR

Introduction

Zoryl-M is a prescription medication that contains two active ingredients: Glimepiride and Metformin. It is commonly prescribed to manage blood sugar levels in patients with type 2 diabetes.

Uses

Zoryl-M is primarily used to control blood sugar levels in individuals with type 2 diabetes. It helps to lower and regulate blood glucose levels by improving insulin sensitivity and reducing the amount of glucose produced by the liver.

Dosage and Administration

The dosage of Zoryl-M may vary depending on the individual’s condition and response to treatment. Follow the instructions provided by your healthcare professional. Generally, the recommended starting dose is one tablet taken once daily, preferably with a meal.

Mechanism of Action

Glimepiride, one of the active ingredients in Zoryl-M, belongs to a class of medications called sulfonylureas. It works by stimulating the pancreas to produce more insulin and helps the body use insulin more effectively. Metformin, the other active ingredient, is a biguanide that reduces the amount of glucose produced by the liver and improves the body’s response to insulin.

Side Effects

Common side effects may include nausea, diarrhea, stomach upset, headache, and dizziness. These side effects are usually mild and temporary. However, if you experience any persistent or severe side effects, consult your healthcare professional.

In rare cases, Zoryl-M may cause serious side effects such as lactic acidosis, a rare but potentially life-threatening condition. Symptoms of lactic acidosis may include weakness, muscle pain, difficulty breathing, unusual tiredness, and stomach discomfort. If you experience any of these symptoms, seek immediate medical attention.

Drug Interactions

Zoryl-M may interact with other medications, including certain antibiotics, antifungal drugs, and blood thinners. Inform your healthcare professional about all the medications you are currently taking, including prescription drugs, over-the-counter medications, and herbal supplements. They can determine if any potential interactions may occur and adjust your treatment plan accordingly.

Precautions

Before taking Zoryl-M, inform your healthcare professional about any medical conditions you have, especially if you have a history of kidney or liver problems. This medication should not be used in individuals with severe kidney or liver impairment.

Zoryl-M may also interact with alcohol and increase the risk of developing lactic acidosis. It is advisable to limit or avoid alcohol consumption while taking this medication.

Storage

Zoryl-M should be stored at room temperature, away from moisture and direct sunlight. Keep it out of the reach of children and pets. Do not use the medication if it has expired or if the packaging is damaged.

Patient Tips

• Take Zoryl-M as prescribed by your healthcare professional. Do not adjust the dosage or stop taking the medication without consulting them.
• monitor your blood sugar levels regularly while taking this medication. Follow your healthcare professional’s advice regarding blood sugar testing.
• Maintain a healthy lifestyle, including a balanced diet and regular exercise, to help manage your blood sugar levels effectively.
• If you experience any unusual symptoms or have concerns about the medication, discuss them with your healthcare professional. They can provide guidance and support throughout your treatment journey.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Glimepiride: medicine to treat type 2 diabetes (NHS UK) [Accessed 4 Jun. 2024] (online) Available at:
• Glimepiride 1 mg tablets (Health Professionals SmPC) Available at:
• Glimepiride (Drugs.com) [Accessed 6 Jun. 2024] (online) Available at:
• glimepiride (amaryl) (RX) [Accessed 9 Jun. 2024] (online) Available at:
• Glimepiride (MedlinePlus) [Accessed 25 Jun. 2024] (online) Available at:
• Ridderstråle M, Andersen KR, Zeller C, Kim G, Woerle HJ, Broedl UC; EMPA-REG H2H-SU trial investigators. Comparison of empagliflozin and glimepiride as add-on to metformin in patients with type 2 diabetes: a 104-week randomised, active-controlled, double-blind, phase 3 trial. Lancet Diabetes Endocrinol. 2014 Sep;2(9):691-700. doi: 10.1016/S2213-8587(14)70120-2. Epub 2014 Jun 16. [Accessed 3 Jun. 2024] Available at: