Zotide 600mcg Injection

Introduction

Zotide is a medication that contains the active ingredient Teriparatide. It is available under the brand name Zotide. Teriparatide is a synthetic form of parathyroid hormone, which helps to regulate calcium and phosphate levels in the body. This medication is primarily used for the treatment of osteoporosis in postmenopausal women and in men at high risk of fractures.

Uses

Zotide is prescribed to treat osteoporosis, a condition characterized by weakened bones that are more prone to fractures. It is specifically indicated for use in postmenopausal women with severe osteoporosis, as well as in men with osteoporosis who are at high risk of fractures. This medication helps to increase bone density and reduce the risk of fractures.

Dosage and Administration

Zotide is administered by subcutaneous injection, usually once daily. The recommended dose is 20 micrograms (mcg) per day. The injection should be given in the thigh or abdomen, and the injection site should be rotated to avoid irritation. Follow the instructions provided by your healthcare professional regarding the proper administration technique.

Mechanism of Action

Teriparatide, the active ingredient in Zotide, works by stimulating bone formation. It does this by activating osteoblasts, which are the cells responsible for building new bone tissue. By increasing bone formation, Teriparatide helps to strengthen the bones and reduce the risk of fractures. It also increases the intestinal absorption of calcium and promotes the renal reabsorption of calcium, leading to improved calcium levels in the body.

Side Effects

Common side effects may include nausea, dizziness, headache, and injection site reactions such as pain or redness. These side effects are usually mild and go away on their own. However, if you experience any severe or persistent side effects, such as difficulty breathing, chest pain, or allergic reactions, seek medical attention immediately.

Drug Interactions

Before using Zotide. Inform your healthcare professional about all the medications you are taking, including prescription drugs, over-the-counter medications, and herbal supplements. Some medications can interact with Teriparatide, potentially affecting its effectiveness or increasing the risk of side effects. It is particularly important to avoid using Zotide with other medications that affect bone metabolism, such as bisphosphonates or calcitonin.

Precautions

There are certain precautions to consider when using Zotide. This medication is not recommended for use in individuals with a history of bone cancer or Paget’s disease of the bone. Inform your healthcare professional if you have any other medical conditions, such as kidney disease or hypercalcemia. Additionally, avoid alcohol and tobacco while using this medication, as they can interfere with its effectiveness.

Storage

Zotide should be stored in the refrigerator at a temperature between 2°C and 8°C (36°F and 46°F). Do not freeze the medication. Keep it in the original packaging and protect it from light. Do not use the medication if it has expired or if the solution appears discolored or contains particles.

Patient Tips

• Follow the instructions provided by your healthcare professional regarding the administration of Zotide.
• If you miss a dose, take it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule.
• maintain a healthy diet rich in calcium and vitamin D while using this medication.
• Report any unusual or persistent side effects to your healthcare professional.
• Keep all follow-up appointments with your healthcare professional to monitor your progress and adjust your treatment if necessary.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Forsteo 20 micrograms/80 microlitres solution for injection in pre-filled pen (Health Professionals SmPC) Available at:
• Teriparatide (Drugs.com) [Accessed 27 Jun. 2024] (online) Available at:
• teriparatide 20 mcg/dose (620 mcg/2.48 ml) subcutaneous pen injector parathyroid hormone (RX) [Accessed 2 Jun. 2024] (online) Available at:
• Teriparatide Injection (MedlinePlus) [Accessed 24 Jun. 2024] (online) Available at:
• Leder BZ, Tsai JN, Uihlein AV, Wallace PM, Lee H, Neer RM, Burnett-Bowie SA. Denosumab and teriparatide transitions in postmenopausal osteoporosis (the DATA-Switch study): extension of a randomised controlled trial. Lancet. 2015 Sep 19;386(9999):1147-55. doi: 10.1016/S0140-6736(15)61120-5. Epub 2015 Jul 2. [Accessed 11 Jun. 2024] Available at: