Zuratin 20mg Soft Gelatin Capsule

Introduction

Zuratin is a prescription medication that contains the active ingredient isotretinoin. It is available under the brand name Zuratin. This medication is primarily used to treat severe acne that has not responded to other treatments.

Uses

Zuratin is prescribed for the treatment of severe nodular acne. It is used when other treatments, such as topical creams or antibiotics, have not been effective in managing the condition. Nodular acne is characterized by the presence of large, painful, and deep acne lesions.

Dosage and Administration

The dosage of Zuratin will vary depending on the severity of the acne and the individual patient’s response to the medication. Follow your healthcare provider’s instructions regarding the dosage and duration of treatment.

Generally, the recommended starting dose for Zuratin is 0.5 to 1 mg per kilogram of body weight per day, taken in two divided doses with food for 15 to 20 weeks. The dosage may be adjusted by your healthcare provider based on your response to the medication.

Take the capsules with a meal to enhance absorption and reduce the risk of stomach upset. Swallow the capsules whole and do not crush or chew them.

Mechanism of Action

Isotretinoin, the active ingredient in Zuratin, belongs to a class of medications called retinoids. It works by reducing the production of sebum (oil) in the skin, inhibiting the growth of acne-causing bacteria, and reducing inflammation. This helps to improve the appearance of acne and prevent the formation of new acne lesions.

Side Effects

Common side effects may include dry skin, dry lips, dry eyes, and nosebleeds. These side effects are usually mild and improve as the treatment continues.

However, some side effects may be more serious and require medical attention. These can include severe skin rash, severe abdominal pain, mood changes, or signs of liver problems such as yellowing of the skin or eyes, dark urine, or persistent nausea and vomiting.

If you experience any of these serious side effects or have concerns about any side effects, contact your healthcare provider immediately.

Drug Interactions

Zuratin may interact with other medications, including certain antibiotics, oral contraceptives, and vitamin A supplements. Inform your healthcare provider about all the medications you are currently taking, including prescription drugs, over-the-counter medications, and herbal supplements.

Some drug interactions may increase the risk of side effects or reduce the effectiveness of Zuratin. Your healthcare provider will consider these potential interactions when prescribing this medication.

Precautions

Before starting treatment with Zuratin, discuss your medical history and any pre-existing conditions with your healthcare provider. Inform them if you have a history of depression, liver disease, or high blood lipid levels.

Zuratin should not be used during pregnancy or if you are planning to become pregnant, as it can cause severe birth defects. Use effective contraception while taking this medication and for at least one month after stopping treatment.

Additionally, avoid donating blood while taking Zuratin and for one month after discontinuing the medication, as it may be harmful to pregnant women who receive blood containing isotretinoin.

Storage

Patient Tips

• Follow your healthcare provider’s instructions regarding the dosage and duration of treatment with Zuratin.
• Take the capsules with a meal to enhance absorption and reduce the risk of stomach upset.
• Use a moisturizer and lip balm to manage dry skin and lips, which are common side effects of this medication.
• Protect your skin from excessive sunlight and use sunscreen with a high SPF.
• Avoid waxing or undergoing cosmetic procedures that may irritate the skin while taking Zuratin.
• If you wear contact lenses and experience dry eyes, consider using artificial tears or wearing glasses instead.
• Inform your healthcare provider about any changes in mood or any other concerns you may have during treatment with Zuratin.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Acne – Treatment (NHS UK) [Accessed 29 Jun. 2024] (online) Available at:
• Isotretinoin 10 mg soft capsules (Health Professionals SmPC) Available at:
• Isotretinoin (Drugs.com) [Accessed 28 Jun. 2024] (online) Available at:
• Isotretinoin (MedlinePlus) [Accessed 22 Jun. 2024] (online) Available at:
• Huang YC, Cheng YC. Isotretinoin treatment for acne and risk of depression: A systematic review and meta-analysis. J Am Acad Dermatol. 2017 Jun;76(6):1068-1076.e9. doi: 10.1016/j.jaad.2016.12.028. Epub 2017 Mar 11. [Accessed 28 Jun. 2024] Available at: