Zyciderm Plus Cream

Introduction

Zyciderm Plus is a prescription medication that contains a combination of active ingredients: Ofloxacin, Clobetasol, Miconazole, Terbinafine, and Dexpanthenol. It is primarily used for the treatment of various skin infections and inflammatory conditions.

Uses

Zyciderm Plus is indicated for the treatment of skin infections caused by certain types of bacteria and fungi. It is commonly prescribed for conditions such as bacterial skin infections, fungal skin infections, and inflammatory skin conditions like eczema and psoriasis.

Dosage and Administration

follow the instructions provided by your healthcare professional regarding the dosage and administration of Zyciderm Plus. Typically, a thin layer of the cream should be applied to the affected area(s) of the skin twice a day, unless otherwise directed by your doctor. It is recommended to wash and dry the affected area before applying the cream. Avoid contact with eyes, mouth, and other mucous membranes. Be sure to wash your hands thoroughly after each application.

Mechanism of Action

Zyciderm Plus contains a combination of active ingredients that work together to combat skin infections and reduce inflammation. Ofloxacin is a fluoroquinolone antibiotic that inhibits the growth of bacteria by interfering with their DNA replication. Clobetasol is a high-potency corticosteroid that helps reduce inflammation and itching. Miconazole and Terbinafine are antifungal agents that target and eliminate fungal infections. Dexpanthenol, also known as provitamin B5, helps moisturize and soothe the skin.

Side Effects

Common side effects may include mild skin irritation, itching, or redness at the application site. These effects are usually temporary and should subside as your skin adjusts to the medication. However, if you experience severe or persistent side effects, such as blistering, severe skin rash, or signs of an allergic reaction (e.g., difficulty breathing, swelling of the face or throat), seek immediate medical attention.

Drug Interactions

inform your healthcare professional about all the medications you are currently taking, including prescription drugs, over-the-counter medications, and herbal supplements. Certain medications may interact with Zyciderm Plus, potentially affecting its efficacy or increasing the risk of side effects. Be cautious when using other topical medications or creams in the same area, as they may interfere with the absorption or action of Zyciderm Plus. Always consult with your doctor or pharmacist before starting or stopping any medications alongside Zyciderm Plus.

Precautions

Before using Zyciderm Plus, inform your healthcare professional about any known allergies to the active ingredients or any other substances. Discuss your medical history, especially if you have a history of skin sensitivity, open wounds, or any other skin conditions. Use caution when applying the cream to the face, as certain active ingredients may cause skin thinning or other adverse effects in this area. Avoid prolonged use of Zyciderm Plus without medical supervision, as it may lead to skin thinning or other topical steroid-related side effects.

Storage

Patient Tips

• Follow the prescribed dosage and administration instructions provided by your healthcare professional.
• Wash and dry the affected area before applying the cream.
• Avoid contact with eyes, mouth, and other mucous membranes.
• Wash your hands thoroughly after each application.
• If you experience severe or persistent side effects, seek medical attention.
• Inform your healthcare professional about all medications you are currently taking.
• Discuss any known allergies or skin conditions with your doctor before using Zyciderm Plus.
• Use caution when applying the cream to the face.
• Store the cream at room temperature, away from heat and moisture.
• Do not use the cream if it has expired.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Clobetasol: a steroid medicine to treat swelling and itching (NHS UK) [Accessed 4 Jun. 2024] (online) Available at:
• CLARELUX 500 microgram/g cutaneous foam in pressurised container (Health Professionals SmPC) Available at:
• Clobetasol Topical (Drugs.com) [Accessed 12 Jun. 2024] (online) Available at:
• clobetasol 0.05 % cream -gauze 4″ x 4″-silicone adhesive topical kit (RX) [Accessed 30 Jun. 2024] (online) Available at:
• Clobetasol Topical (MedlinePlus) [Accessed 3 Jun. 2024] (online) Available at:
• Pels R, Sterry W, Lademann J. Clobetasol propionate–where, when, why? Drugs Today (Barc). 2008 Jul;44(7):547-57. doi: 10.1358/dot.2008.44.7.1122221. [Accessed 26 Jun. 2024] Available at: