Zyra-L Capsule SR

Introduction

Zyra-L SR is a prescription medication that combines two active ingredients: Levosulpiride and Rabeprazole. Levosulpiride is a dopamine antagonist, while Rabeprazole belongs to the class of proton pump inhibitors. This medication is commonly prescribed under the brand name Zyra-L SR for the management of certain gastrointestinal conditions.

Uses

Zyra-L SR is primarily used to treat various gastrointestinal disorders. It is commonly prescribed for the following conditions:

• Gastroesophageal reflux disease (GERD): Zyra-L SR helps alleviate symptoms such as heartburn, acid reflux, and regurgitation by reducing the production of stomach acid.
• Functional dyspepsia: This medication can help relieve symptoms of indigestion, bloating, and discomfort associated with functional dyspepsia.
• Peptic ulcers: Zyra-L SR aids in the healing of peptic ulcers by reducing gastric acid secretion and promoting the protective lining of the stomach.

Dosage and Administration

• The dosage of Zyra-L SR may vary depending on the specific condition being treated and individual patient factors. Follow the instructions provided by your healthcare professional.
• The capsules should be swallowed whole with a glass of water, preferably before meals.
• It is recommended to take Zyra-L SR at the same time each day for optimal effectiveness.
• Do not crush or chew the capsules, as it may interfere with the controlled release mechanism.

Mechanism of Action

Zyra-L SR works through the combined action of its active ingredients, Levosulpiride and Rabeprazole.

• Levosulpiride acts as a dopamine antagonist, which helps regulate the movement of food through the digestive system. It also increases the release of certain digestive enzymes, improving digestion.
• Rabeprazole belongs to the class of proton pump inhibitors, which inhibit the secretion of gastric acid by blocking the enzyme responsible for acid production in the stomach. This helps reduce acid-related symptoms and promotes the healing of peptic ulcers.

Side Effects

Common side effects may include:

• Nausea
• Headache
• Diarrhea
• Abdominal pain
• Dizziness

Serious side effects are rare but may include:

• Allergic reactions (rash, itching, swelling)
• Severe abdominal pain
• Difficulty breathing
• Irregular heartbeat

If you experience any of these serious side effects or any other unusual symptoms, seek immediate medical attention.

Drug Interactions

Zyra-L SR may interact with certain medications, potentially affecting their efficacy or increasing the risk of side effects. Inform your healthcare professional about all the medications you are taking, including prescription, over-the-counter, and herbal products. Some common drug interactions with Zyra-L SR include:

• Anticoagulants (e.g., warfarin): Increased risk of bleeding.
• Antiplatelet drugs (e.g., clopidogrel): Decreased effectiveness.
• Certain antidepressants and antipsychotics: Increased risk of certain side effects.

This is not an exhaustive list, and other interactions may occur. Always consult your healthcare professional for personalized advice.

Precautions

Before taking Zyra-L SR, consider the following precautions:

• Inform your healthcare professional about any known allergies or sensitivities to Levosulpiride, Rabeprazole, or any other medications.
• If you have a history of liver or kidney disease, discuss this with your healthcare professional, as dosage adjustments may be necessary.
• Zyra-L SR should be used with caution in elderly patients, as they may be more susceptible to side effects.
• Avoid consuming alcohol while taking this medication, as it may increase the risk of certain side effects.
• Inform your healthcare professional about all the medications you are taking to prevent potential drug interactions.

Storage

Zyra-L SR should be stored in a cool, dry place away from direct sunlight. Keep the medication out of reach of children and pets. Do not use the medication if it has exceeded the expiration date printed on the packaging.

Patient Tips

• Take Zyra-L SR as prescribed by your healthcare professional. Do not adjust the dosage or stop taking the medication without consulting your doctor.
• If you forget to take a dose, take it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule.
• Maintain a healthy lifestyle by following a balanced diet, avoiding trigger foods, and practicing stress management techniques to help manage gastrointestinal conditions.
• If you experience any bothersome or persistent side effects, discuss them with your healthcare professional.
• Attend regular follow-up appointments with your doctor to monitor your progress and adjust the treatment plan if necessary.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Rabeprazole: medicine to lower stomach acid (NHS UK) [Accessed 30 Jun. 2024] (online) Available at:
• PARIET 10mg (Health Professionals SmPC) Available at:
• Levosulpiride (International database) (Drugs.com) [Accessed 7 Jun. 2024] (online) Available at:
• rabeprazole sodium (RX) [Accessed 26 Jun. 2024] (online) Available at:
• Rabeprazole (MedlinePlus) [Accessed 30 Jun. 2024] (online) Available at:
• Arshad A, Irfan M, Inam M, Hussain NHN, Ismail SB. Levosulpiride for Premature Ejaculation: A Systematic Review and Meta-Analysis. Am J Mens Health. 2022 Sep-Oct;16(5):15579883221124832. doi: 10.1177/15579883221124832. [Accessed 8 Jun. 2024] Available at: