Captopril, Hydrochlorothiazide

Captopril Hydrochlorothiazide is a combination medication that consists of two active ingredients: Captopril, an ACE (angiotensin-converting enzyme) inhibitor, and Hydrochlorothiazide, a thiazide diuretic. This medication is used to treat hypertension (high blood pressure) by relaxing blood vessels and reducing the amount of fluid in the body.
Captopril works by inhibiting the angiotensin-converting enzyme, which prevents the formation of angiotensin II, a potent vasoconstrictor. This results in widening of blood vessels and a decrease in peripheral resistance, leading to a reduction in blood pressure. Hydrochlorothiazide, on the other hand, promotes the excretion of sodium and water by the kidneys, which reduces fluid volume and also contributes to lowering blood pressure.
This combination medication is typically prescribed for patients who require both a vasodilator and a diuretic for optimal blood pressure control. It may also be used in those with heart failure, as it can help reduce the workload on the heart by decreasing the fluid overload and improving overall cardiac function.
Captopril Hydrochlorothiazide is usually taken once or twice daily, as directed by a healthcare professional. Follow the prescribed dosage and schedule, as well as any other instructions given by the prescribing physician. This medication may cause side effects such as dizziness, dry mouth, or increased sensitivity to sunlight. Report any adverse reactions or worsening of symptoms to a healthcare provider promptly.