Clopidogrel

Clopidogrel is an oral antiplatelet medication used for the prevention of blood clots in patients with certain cardiovascular conditions. It is particularly effective in reducing the risk of ischemic events, such as heart attacks and strokes, in individuals who have already experienced one or are at high risk.
Clopidogrel works by irreversibly inhibiting the P2Y12 receptor on platelets, a type of blood cell involved in clot formation. By blocking this receptor, clopidogrel prevents platelets from sticking together and forming clots, thereby reducing the likelihood of arterial blockages and thrombotic complications.
The medication is often prescribed in combination with aspirin for optimal antiplatelet effect, particularly in patients undergoing percutaneous coronary intervention (PCI) or those with a history of myocardial infarction, stroke, or peripheral artery disease. Clopidogrel is typically administered as a 75 mg loading dose followed by a maintenance dose of 75 mg daily.
While clopidogrel is generally well-tolerated, it may cause side effects such as bleeding, including gastrointestinal and cerebral hemorrhage. Patients should be cautioned about the potential risks and benefits of the medication, and should report any signs of abnormal bleeding to their healthcare provider.