Tacrolimus

Tacrolimus is an immunosuppressive medication, belonging to a class of drugs known as calcineurin inhibitors. It is primarily used in the prevention of organ rejection, specifically in patients who have undergone transplant surgery. Tacrolimus works by suppressing the immune system, preventing it from attacking the transplanted organ. This medication is available in both oral and topical forms, with the oral formulation being more commonly used for organ transplant patients.
Tacrolimus is often prescribed as part of a combination therapy, alongside other immunosuppressive agents like corticosteroids and mycophenolate mofetil. The combination of these medications helps to achieve a more effective and balanced suppression of the immune system, reducing the risk of organ rejection while minimizing the potential side effects of each individual drug.
The use of tacrolimus requires close monitoring by healthcare professionals, as it can have significant side effects if not used correctly. Common side effects include high blood pressure, swelling, tremors, and an increased risk of infections. Regular blood tests are necessary to ensure that the medication is being used at an appropriate dose, as both underdosing and overdosing can lead to complications.