Proguanil

Proguanil is an antimalarial medication used to prevent and treat malaria, a disease caused by parasites transmitted through the bite of infected mosquitoes. It is effective against the Plasmodium vivax, Plasmodium ovale, and Plasmodium malariae species.
Proguanil works by inhibiting the growth of the malaria parasite within the human host, thereby preventing the onset of clinical symptoms. It is often used in combination with other antimalarial drugs, such as chloroquine or atovaquone-proguanil, to provide broader-spectrum protection against different malaria species.
For prevention, proguanil is typically administered daily, starting one to two weeks before entering a malaria-endemic area and continuing for four weeks after leaving. In treatment, the recommended dose depends on the severity of the infection and the patient’s age and weight. It is important to follow the prescribed dosage and complete the course of treatment to ensure the parasite is completely eliminated.
Proguanil is generally well-tolerated, but potential side effects may include gastrointestinal symptoms, headaches, dizziness, and skin rashes. In rare cases, it may cause more severe reactions, such as blood disorders or liver problems. Patients should consult their healthcare provider if they experience any adverse effects or develop new symptoms while taking proguanil.
To ensure the safe and effective use of proguanil, adhere to the prescribed dosage regimen and follow the guidance of a healthcare professional. Travelers to malaria-endemic regions should also take additional precautions, such as using insect repellent and sleeping under mosquito nets, to minimize the risk of infection.