Equine Rabies Immunoglobulin

Equine Rabies Immunoglobulin (ERIG) is a specialized medication derived from the blood plasma of immunized horses. It is used as a post-exposure prophylaxis for individuals who have been exposed to rabies virus, either through a bite, scratch, or direct contact with infected animals.
The primary function of ERIG is to provide immediate passive immunity by introducing pre-formed antibodies into the exposed person’s bloodstream. These antibodies help neutralize the virus, preventing it from replicating and spreading throughout the body. The medication is administered as early as possible after exposure, ideally within 24 to 72 hours, to maximize its effectiveness in preventing rabies infection.
ERIG is not a substitute for rabies vaccination. In addition to receiving ERIG, the exposed individual must also undergo a full course of rabies vaccination to establish active immunity and ensure long-term protection against the virus.