Imipenem, Cilastatin

Imipenem and Cilastatin is a combination antibiotic used to treat severe bacterial infections. Imipenem is a carbapenem antibiotic, a class of drugs known for their potent activity against a wide range of bacteria. Cilastatin, on the other hand, is an inactive component that helps protect the kidneys from the nephrotoxic effects of imipenem.
This medication is used to treat infections caused by susceptible bacteria, such as those affecting the lungs, abdomen, urinary tract, and bloodstream. Imipenem and Cilastatin are particularly effective against gram-negative and gram-positive bacteria, as well as certain anaerobic bacteria. Due to its broad-spectrum activity, this combination medication is often reserved for severe infections that have not responded to other antibiotics.
Imipenem and Cilastatin should be used with caution, as it can cause serious side effects, including seizures and kidney damage. Patients with a history of seizures or kidney problems should discuss the risks and benefits of this medication with their healthcare provider before starting treatment. Additionally, this medication should only be prescribed by healthcare professionals experienced in the treatment of severe bacterial infections.