Suxamethonium

Suxamethonium, also known as Succinylcholine, is a rapid-acting neuromuscular blocking agent. It is a synthetic quaternary ammonium compound that acts as a depolarizing muscle relaxant. Suxamethonium is commonly used in medical procedures that require temporary paralysis of the patient’s muscles, such as during surgery or certain diagnostic tests.
The primary use of Suxamethonium is for inducing skeletal muscle relaxation and facilitating intubation in patients undergoing general anesthesia. It is also employed for the rapid control of muscle spasms in conditions like tetanus or status epilepticus. Additionally, Suxamethonium is used in the diagnosis of myasthenia gravis, a neuromuscular disorder characterized by muscle weakness and fatigue.
Suxamethonium acts by binding to nicotinic acetylcholine receptors at the neuromuscular junction, causing a rapid depolarization of the motor endplate. This leads to a temporary paralysis of the skeletal muscles, allowing for easier intubation and the performance of various medical procedures. The effects of Suxamethonium are typically short-lived, with muscle function returning to normal within minutes of administration.
Note that Suxamethonium should be used with caution in patients with certain pre-existing conditions, such as hyperkalemia, burns, or a history of malignant hyperthermia. The medication should also be administered under the supervision of a qualified healthcare professional, as it can cause side effects like muscle pain, increased heart rate, and high blood pressure.