Domperidone, Cinnarizine

Domperidone Cinnarizine is a combination medication that consists of two active ingredients: Domperidone, a dopamine antagonist, and Cinnarizine, a combination of cinnarizing and cyclizine, which is an antihistamine and anticholinergic agent. This medication is used primarily to treat symptoms associated with motion sickness, such as dizziness, nausea, and vomiting.
The role of Domperidone in the medication is to block dopamine receptors in the brain, specifically D2 receptors, which helps in reducing the sensation of nausea and vomiting. On the other hand, Cinnarizine works by inhibiting histamine H1 and muscarinic M1 receptors, which helps to alleviate the effects of motion sickness and improve overall comfort during travel.
In addition to its use in motion sickness, Domperidone Cinnarizine may also be prescribed to treat vertigo, dizziness, and imbalance caused by issues with the inner ear or the central nervous system. Note that this medication should only be taken under the supervision of a healthcare professional, and individuals should follow the prescribed dosage carefully to avoid any potential side effects or adverse reactions.