Flunarizine, Domperidone

Flunarizine and Domperidone are two medications that are often used in combination to treat various gastrointestinal and vestibular disorders. Flunarizine is a dopamine receptor antagonist that helps to control nausea and vomiting by reducing the activity of the vomiting center in the brain. Domperidone, on the other hand, is a dopamine receptor antagonist that works by increasing the motility of the gastrointestinal tract and decreasing the tone of the lower esophageal sphincter, thus helping to alleviate symptoms of gastroesophageal reflux disease (GERD) and other gastrointestinal conditions.
The combination of Flunarizine and Domperidone is commonly used to treat motion sickness, vertigo, and other vestibular disorders, such as Meniere’s disease. The medications work together to reduce nausea, vomiting, and dizziness, providing relief for individuals who experience these symptoms due to inner ear problems or motion sickness. This combination therapy is also used to treat gastroparesis, a condition where the stomach takes too long to empty its contents, leading to symptoms like nausea, vomiting, and abdominal pain.
When prescribing this combination medication, healthcare professionals will consider factors such as the severity of the patient’s symptoms, other underlying medical conditions, and potential drug interactions. It is important for patients to follow their healthcare provider’s instructions and to report any adverse effects or worsening of symptoms promptly.