Teriflunomide

Teriflunomide is an immunosuppressive medication belonging to the class of drugs called pyrimidine synthesis inhibitors. It is primarily used for the treatment of relapsing forms of multiple sclerosis (MS), an autoimmune disorder that affects the central nervous system. The medication works by selectively inhibiting the enzyme dihydroorotate dehydrogenase, which in turn reduces the synthesis of pyrimidine nucleotides. This leads to the suppression of T-lymphocyte proliferation and reduction of inflammation, slowing down the progression of MS symptoms. Teriflunomide has a long half-life, allowing for once-daily dosing, and is usually prescribed as an adjunct to other disease-modifying therapies for MS. However, be aware of the potential risks associated with this medication, including hepatic injury, teratogenicity, and serious blood disorders. Regular monitoring is necessary to ensure patient safety during treatment with teriflunomide.