Abendaz Suspension

Introduction

Abendaz is a prescription medication that contains two active ingredients: Amoxicillin and Clavulanic Acid. Amoxicillin is a type of antibiotic, while Clavulanic Acid is a beta-lactamase inhibitor that helps prevent bacteria from becoming resistant to the antibiotic. This medication is available in suspension form and is commonly prescribed under the brand name Abendaz.

Uses

Abendaz is primarily used to treat bacterial infections caused by susceptible organisms. It is commonly prescribed for the treatment of respiratory tract infections, such as bronchitis and pneumonia, as well as skin and soft tissue infections, urinary tract infections, and certain types of dental infections. Note that this medication is only effective against bacterial infections and will not work for viral infections, such as the common cold or flu.

Dosage and Administration

The dosage of Abendaz will vary depending on the severity of the infection, the patient’s age, and their overall health condition. Follow the dosage instructions provided by your healthcare provider. The suspension should be shaken well before each use to ensure proper distribution of the medication. It is usually taken orally, either with or without food. Complete the full course of treatment as prescribed, even if you start feeling better before finishing the medication.

Mechanism of Action

Amoxicillin, one of the active ingredients in Abendaz, belongs to the class of antibiotics known as penicillins. It works by interfering with the bacterial cell wall synthesis, leading to the destruction of the bacteria. Clavulanic Acid, the other active ingredient, helps prevent the breakdown of Amoxicillin by certain bacteria that produce an enzyme called beta-lactamase. By inhibiting this enzyme, Clavulanic Acid enhances the effectiveness of Amoxicillin against a broader range of bacteria.

Side Effects

Abendaz may cause some side effects in certain individuals. Common side effects may include nausea, vomiting, diarrhea, and skin rash. These side effects are usually mild and resolve on their own. However, if they persist or worsen, contact your healthcare provider. In rare cases, Abendaz may cause more serious side effects, such as severe allergic reactions, liver problems, and blood disorders. If you experience any unusual symptoms, such as difficulty breathing, yellowing of the skin or eyes, or unusual bleeding or bruising, seek medical attention immediately.

Drug Interactions

inform your healthcare provider about all the medications you are currently taking, including prescription drugs, over-the-counter medications, and herbal supplements. Certain medications may interact with Abendaz and affect its effectiveness or increase the risk of side effects. For example, this medication may interact with certain antibiotics, anticoagulants, and medications used to treat gout. Your healthcare provider will consider these potential interactions when prescribing Abendaz and may adjust the dosage or recommend alternative treatments if necessary.

Precautions

Before taking Abendaz, inform your healthcare provider about any allergies you may have, especially to penicillin or cephalosporin antibiotics. Additionally, inform your healthcare provider about any medical conditions you have, such as liver disease, kidney disease, or a history of gastrointestinal problems. This medication may not be suitable for everyone, and your healthcare provider will consider these factors before prescribing it. Avoid alcohol consumption while taking Abendaz, as it may increase the risk of certain side effects.

Storage

Abendaz should be stored at room temperature, away from direct sunlight and moisture. Keep the medication out of reach of children and pets. Do not freeze the suspension or store it in the bathroom, as moisture and extreme temperatures can affect its stability. If you have any unused or expired medication, dispose of it properly according to local regulations or consult your pharmacist for guidance.

Patient Tips

• Take Abendaz exactly as prescribed by your healthcare provider.
• Shake the suspension well before each use to ensure proper mixing of the medication.
• Complete the full course of treatment, even if you start feeling better before finishing the medication.
• If you miss a dose, take it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule.
• Do not share this medication with others, as it may not be suitable for their condition.
• If you experience any unusual symptoms or have concerns about the medication, contact your healthcare provider.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Common questions about co-amoxiclav (NHS UK) [Accessed 13 Jun. 2024] (online) Available at:
• Augmentin Duo 400/57 powder for oral suspension (mixed fruit flavour) (Health Professionals SmPC) Available at:
• Clavulanic Acid (International database) (Drugs.com) [Accessed 15 Jun. 2024] (online) Available at:
• Amoxicillin and Clavulanic Acid (MedlinePlus) [Accessed 9 Jun. 2024] (online) Available at:
• Keij FM, Kornelisse RF, Hartwig NG, van der Sluijs-Bens J, van Beek RHT, van Driel A, van Rooij LGM, van Dalen-Vink I, Driessen GJA, Kenter S, von Lindern JS, Eijkemans M, Stam-Stigter GM, Qi H, van den Berg MM, Baartmans MGA, van der Meer-Kappelle LH, Meijssen CB, Norbruis OF, Heidema J, van Rossem MC, den Butter PCP, Allegaert K, Reiss IKM, Tramper-Stranders GA. Efficacy and safety of switching from intravenous to oral antibiotics (amoxicillin-clavulanic acid) versus a full course of intravenous antibiotics in neonates with probable bacterial infection (RAIN): a multicentre, randomised, open-label, non-inferiority trial. Lancet Child Adolesc Health. 2022 Nov;6(11):799-809. doi: 10.1016/S2352-4642(22)00245-0. Epub 2022 Sep 9. [Accessed 30 Jun. 2024] Available at: