Introduction
Aceflip R is a prescription medication that contains the active ingredients Aceclofenac and Rabeprazole. It is available in capsule form and is commonly used for the treatment of certain conditions related to inflammation and stomach acid.
Uses
Aceflip R is primarily prescribed for the following conditions:
- Pain and inflammation: It helps to relieve pain and reduce inflammation in conditions such as arthritis, osteoarthritis, and ankylosing spondylitis.
- Gastroesophageal reflux disease (GERD): It is also used to treat symptoms of GERD, such as heartburn and acid reflux.
Dosage and Administration
The recommended dosage of Aceflip R may vary depending on the specific condition being treated and the individual’s response to the medication. Follow the instructions provided by your healthcare professional. Generally, the usual dosage is one capsule taken orally once daily, preferably before a meal.
Mechanism of Action
Aceclofenac, one of the active ingredients in Aceflip R, belongs to a class of medications called nonsteroidal anti-inflammatory drugs (NSAIDs). It works by reducing the production of certain chemicals in the body that are responsible for pain and inflammation.
Rabeprazole, the other active ingredient, is a proton pump inhibitor (PPI) that reduces the production of stomach acid. By reducing the amount of acid produced, it helps to relieve symptoms of GERD and protect the stomach lining from damage.
Side Effects
Common side effects may include:
- Nausea
- Abdominal pain
- Diarrhea
- Headache
If any of these side effects persist or worsen, consult your healthcare professional. In rare cases, Aceflip R may cause more serious side effects, such as severe allergic reactions or gastrointestinal bleeding. If you experience any of these serious side effects, seek immediate medical attention.
Drug Interactions
Aceflip R may interact with certain medications, including:
- Warfarin: This medication used to prevent blood clots may interact with Aceflip R, increasing the risk of bleeding.
- Methotrexate: Concurrent use of Aceflip R and methotrexate may increase the toxicity of methotrexate.
- Other NSAIDs: Taking Aceflip R with other NSAIDs may increase the risk of side effects.
Inform your healthcare professional about all the medications you are taking, including over-the-counter drugs and herbal supplements, to avoid potential drug interactions.
Precautions
Before taking Aceflip R, consider the following precautions:
- Allergies: Inform your healthcare professional if you are allergic to Aceclofenac, Rabeprazole, or any other medications.
- Pregnancy and breastfeeding: Aceflip R should be used with caution during pregnancy and breastfeeding. Consult your healthcare professional for guidance.
- Medical conditions: Inform your healthcare professional if you have a history of stomach ulcers, liver or kidney problems, or any other medical conditions.
Aceflip R may interact with certain medications, including blood thinners and certain antidepressants. Discuss all your medications and medical history with your healthcare professional before starting Aceflip R.
Storage
Aceflip R should be stored at room temperature, away from moisture and heat. Keep it out of reach of children and pets. Do not use the medication if it has expired or if you notice any changes in the appearance of the capsules.
Patient Tips
Here are some additional tips for patients using Aceflip R:
- Take the medication as prescribed by your healthcare professional, and do not exceed the recommended dosage.
- If you forget to take a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule.
- Avoid consuming alcohol while taking Aceflip R, as it may increase the risk of stomach irritation.
- Inform your healthcare professional about any other medications you are taking, including over-the-counter drugs and herbal supplements, to avoid potential interactions.
- If you experience any unusual or persistent symptoms while taking Aceflip R, consult your healthcare professional.
Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.
References
- Rabeprazole: medicine to lower stomach acid (NHS UK) [Accessed 30 Jun. 2024] (online) Available at:
- Aceclofenac 100 mg Film-coated Tablets (Health Professionals SmPC) Available at:
- ACECLOFENAC 100MG TABLETS (Drugs.com) [Accessed 11 Jun. 2024] (online) Available at:
- rabeprazole sodium (RX) [Accessed 26 Jun. 2024] (online) Available at:
- Rabeprazole (MedlinePlus) [Accessed 30 Jun. 2024] (online) Available at:
- Negi S, Tandel N, Sharma P, Kumar R, Tyagi RK. Aceclofenac and methotrexate combination therapy could influence Th1/Th17 axis to modulate rheumatoid-arthritis-induced inflammation. Drug Discov Today. 2023 Aug;28(8):103671. doi: 10.1016/j.drudis.2023.103671. Epub 2023 Jun 16. [Accessed 25 Jun. 2024] Available at:
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