Afitra Cream

Introduction

Afitra is a topical medication that contains the active ingredient Itraconazole. It is available in cream form and is primarily used to treat fungal infections of the skin.

Uses

Afitra is prescribed to treat various skin infections caused by certain types of fungi. It is commonly used to treat fungal infections such as athlete’s foot, jock itch, and ringworm. This medication works by stopping the growth of the fungi responsible for the infection, thereby relieving symptoms and promoting healing.

Dosage and Administration

Before applying Afitra, clean and dry the affected area thoroughly. Apply a thin layer of the cream to the affected skin and gently rub it in until it is absorbed. The cream should be applied once or twice daily, as directed by your healthcare provider. Follow the dosage instructions provided by your healthcare professional and to complete the full course of treatment, even if symptoms improve.

Mechanism of Action

Itraconazole, the active ingredient in Afitra, belongs to a class of medications called azole antifungals. It works by inhibiting the synthesis of ergosterol, a vital component of the fungal cell membrane. By disrupting the fungal cell membrane, Itraconazole effectively kills or slows down the growth of the fungi responsible for the infection.

Side Effects

Common side effects may include skin irritation, redness, itching, or a burning sensation at the site of application. These side effects are usually mild and temporary. However, if you experience any severe or persistent side effects, such as severe skin rash or allergic reactions, seek medical attention immediately.

Drug Interactions

inform your healthcare provider about all the medications you are currently taking, including over-the-counter drugs, herbal supplements, and vitamins. Certain medications may interact with Afitra, potentially affecting its efficacy or increasing the risk of side effects. It is particularly important to avoid concomitant use of Afitra with medications known to prolong the QT interval, such as certain antibiotics, antifungals, and antidepressants. Your healthcare provider can provide you with more specific information on potential drug interactions.

Precautions

Before using Afitra, inform your healthcare provider about any known allergies to medications or any other allergies you may have. Additionally, let your healthcare provider know if you have any other medical conditions, especially liver or kidney disease. Afitra should be used with caution in patients with these conditions.

Storage

Afitra should be stored at room temperature, away from direct sunlight and moisture. Keep the medication out of reach of children and pets. Do not freeze the cream, and do not use it if it has expired.

Patient Tips

Here are some additional tips for patients using Afitra:

• Wash your hands before and after applying the cream to avoid spreading the infection or contaminating other areas.
• Avoid covering the treated area with tight-fitting clothing or dressings, unless otherwise directed by your healthcare provider.
• If you miss a dose, apply it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule.
• If you accidentally swallow the cream, seek medical attention immediately.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Itraconazole 10 mg/ml Concentrate and Solvent for Solution for Infusion (Health Professionals SmPC) Available at:
• Itraconazole (Drugs.com) [Accessed 9 Jun. 2024] (online) Available at:
• itraconazole (RX) [Accessed 4 Jun. 2024] (online) Available at:
• Itraconazole (MedlinePlus) [Accessed 26 Jun. 2024] (online) Available at:
• Piérard GE, Arrese JE, Piérard-Franchimont C. Itraconazole. Expert Opin Pharmacother. 2000 Jan;1(2):287-304. doi: 10.1517/14656566.1.2.287. [Accessed 25 Jun. 2024] Available at: