Ampholip 50mg INJECTION

Introduction

Ampholip is a medication that contains the active ingredient Amphotericin B. It is available in injectable form and is used for the treatment of fungal infections.

Uses

Ampholip is prescribed for the treatment of serious fungal infections. It is commonly used to treat infections caused by fungi such as Candida and Aspergillus. This medication is typically reserved for cases where other antifungal medications have been ineffective or cannot be used.

Dosage and Administration

Ampholip should be administered under the supervision of a healthcare professional. The dosage and duration of treatment will vary depending on the specific infection being treated and the patient’s individual factors. It is usually given intravenously, directly into a vein. The healthcare provider will determine the appropriate dose and frequency for each patient.

Mechanism of Action

Amphotericin B, the active ingredient in Ampholip, works by binding to the cell membrane of the fungus and disrupting its structure. This leads to the leakage of essential cell components, ultimately killing the fungus. It is effective against a wide range of fungal species.

Side Effects

Common side effects of Ampholip may include fever, chills, nausea, vomiting, and headache. These side effects are usually temporary and resolve on their own. However, if any side effects persist or become severe, notify your healthcare provider.

Serious side effects of Ampholip are rare but may include kidney damage, low potassium levels, and allergic reactions. If you experience symptoms such as decreased urine output, swelling, difficulty breathing, or rash, seek medical attention immediately.

Drug Interactions

Ampholip may interact with other medications. Inform your healthcare provider about all the medications you are currently taking, including prescription drugs, over-the-counter medications, and herbal supplements. Some medications, such as certain antibiotics and antifungals, may increase the risk of side effects or affect the effectiveness of Ampholip. Your healthcare provider will carefully consider any potential drug interactions before prescribing this medication.

Precautions

Before using Ampholip, inform your healthcare provider about any known allergies, medical conditions, or medications you are currently taking. This medication should be used with caution in patients with kidney problems or electrolyte imbalances.

Ampholip is contraindicated in individuals who are hypersensitive to Amphotericin B or any of the other ingredients in the formulation. It should not be used during pregnancy unless the potential benefits outweigh the risks.

Storage

Ampholip should be stored in a cool, dry place and protected from light. It should be kept out of reach of children and pets. Do not freeze the medication. Follow the storage instructions provided by your healthcare provider or pharmacist.

Patient Tips

• complete the full course of treatment as prescribed by your healthcare provider, even if you start feeling better.
• Drink plenty of fluids while receiving Ampholip to help prevent dehydration.
• If you miss a dose, contact your healthcare provider for instructions on how to proceed.
• Report any unusual or persistent side effects to your healthcare provider.
• Follow all additional instructions provided by your healthcare provider regarding diet, activity, and other medications while using Ampholip.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Blindness and vision loss (NHS UK) [Accessed 21 Jun. 2024] (online) Available at:
• AmBisome Liposomal 50 mg Powder for dispersion for infusion (Health Professionals SmPC) Available at:
• Amphotericin B (Drugs.com) [Accessed 4 Jun. 2024] (online) Available at:
• amphotericin b chol sulf cmplx suspension for reconstitution (RX) [Accessed 27 Jun. 2024] (online) Available at:
• Amphotericin B Lipid Complex Injection (MedlinePlus) [Accessed 22 Jun. 2024] (online) Available at:
• Hamill RJ. Amphotericin B formulations: a comparative review of efficacy and toxicity. Drugs. 2013 Jun;73(9):919-34. doi: 10.1007/s40265-013-0069-4. [Accessed 17 Jun. 2024] Available at: