Calbona-A Tablet

Introduction

Calbona-A is a prescription medication that contains two active ingredients: Alendronic Acid and Vitamin D3. Alendronic Acid is a type of medication known as a bisphosphonate, which helps to strengthen bones and prevent bone loss. Vitamin D3 is essential for maintaining healthy bones and teeth. Calbona-A is commonly prescribed to individuals with osteoporosis, a condition characterized by weak and brittle bones.

Uses

Calbona-A is primarily used to treat and prevent osteoporosis in postmenopausal women and men at risk of developing the condition. Osteoporosis is a progressive bone disease that increases the risk of fractures. This medication helps to slow down bone loss and increase bone density, reducing the risk of fractures in individuals with osteoporosis.

Dosage and Administration

Calbona-A is typically taken once a week. Follow the instructions provided by your healthcare professional. The tablet should be taken on the same day each week, preferably in the morning, at least 30 minutes before consuming food, beverages, or other medications. It should be swallowed whole with a full glass of plain water while sitting or standing upright. Do not crush, chew, or dissolve the tablet.

Mechanism of Action

Alendronic Acid, one of the active ingredients in Calbona-A, works by inhibiting the activity of cells called osteoclasts, which are responsible for breaking down bone tissue. By reducing the activity of osteoclasts, Alendronic Acid helps to maintain bone density and strength. Vitamin D3, the other active ingredient, aids in the absorption of calcium and promotes bone mineralization, further supporting bone health.

Side Effects

Common side effects may include stomach upset, diarrhea, constipation, headache, and muscle or joint pain. These side effects are usually mild and temporary. However, if you experience any persistent or severe side effects, seek medical attention.

Serious side effects are rare but may include severe bone, joint, or muscle pain, jaw problems (such as jaw pain, swelling, or numbness), and unusual fractures. If you experience any of these serious side effects, stop taking the medication and consult your healthcare professional immediately.

Drug Interactions

inform your healthcare professional about all the medications you are taking, including prescription and over-the-counter medications, as well as any herbal supplements. Some medications may interact with Calbona-A, potentially affecting its effectiveness or increasing the risk of side effects. Common drug interactions include certain medications used to treat osteoporosis (such as other bisphosphonates), calcium supplements, and certain antacids. Always consult your healthcare professional before starting or stopping any medications while taking Calbona-A.

Precautions

Before taking Calbona-A, inform your healthcare professional if you have any allergies, kidney problems, or difficulties swallowing. This medication is not recommended for individuals with certain conditions, such as hypocalcemia (low blood calcium levels), esophageal abnormalities, or inability to stand or sit upright for at least 30 minutes.

Calbona-A may interact with other medications or substances, including certain medications used to treat mineral or vitamin deficiencies, as well as certain medications used to treat seizures or cancer. Discuss all your current medications and medical conditions with your healthcare professional before starting Calbona-A.

Storage

Patient Tips

• Take Calbona-A exactly as prescribed by your healthcare professional. Do not take more or less than the recommended dose.
• maintain an adequate intake of calcium and vitamin D while taking this medication. Your healthcare professional may recommend a specific diet or calcium and vitamin D supplements.
• If you miss a dose, take it as soon as you remember, unless it is close to the time for your next scheduled dose. Do not take two doses at the same time.
• Avoid lying down for at least 30 minutes after taking Calbona-A to prevent irritation of the esophagus.
• If you experience any unusual symptoms or have concerns about the medication, contact your healthcare professional for further guidance.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Alendronic acid: medicine to treat and prevent osteoporosis (NHS UK) [Accessed 1 Jun. 2024] (online) Available at:
• Alendronic Acid 70 mg tablets (Health Professionals SmPC) Available at:
• Colecalciferol (International database) (Drugs.com) [Accessed 5 Jun. 2024] (online) Available at:
• vitamin d3 () [Accessed 10 Jun. 2024] (online) Available at:
• Vitamin D (National Library of Medicine) [Accessed 8 Jun. 2024] (online) Available at:
• Pawade TA, Doris MK, Bing R, White AC, Forsyth L, Evans E, Graham C, Williams MC, van Beek EJR, Fletcher A, Adamson PD, Andrews JPM, Cartlidge TRG, Jenkins WSA, Syed M, Fujisawa T, Lucatelli C, Fraser W, Ralston SH, Boon N, Prendergast B, Newby DE, Dweck MR. Effect of Denosumab or Alendronic Acid on the Progression of Aortic Stenosis: A Double-Blind Randomized Controlled Trial. Circulation. 2021 Jun 22;143(25):2418-2427. doi: 10.1161/CIRCULATIONAHA.121.053708. Epub 2021 Apr 29. [Accessed 5 Jun. 2024] Available at: