Chlorocol Plus Eye Drop

Introduction

Chlorocol Plus is a prescription medication that contains two active ingredients: Chloramphenicol and Dexamethasone. It is available under the brand name Chlorocol Plus. This combination eye drop is primarily used to treat inflammatory eye conditions that are associated with bacterial infections.

Uses

Chlorocol Plus is commonly prescribed to relieve the symptoms of various eye conditions, including:

• Bacterial conjunctivitis: an infection of the conjunctiva, the thin membrane covering the white part of the eye and the inner surface of the eyelids.
• Blepharitis: an inflammation of the eyelids.
• Keratitis: an inflammation of the cornea, the clear front surface of the eye.
• Postoperative inflammation: inflammation that occurs after eye surgery.

Dosage and Administration

follow the instructions provided by your healthcare provider when using Chlorocol Plus. The usual dosage for adults and children is 1 or 2 drops instilled into the affected eye(s), 4 to 6 times daily. The exact dosage and frequency may vary based on the severity of the condition and the individual’s response to treatment.

To administer the eye drops:

• Wash your hands thoroughly before handling the bottle.
• Tilt your head back and look up.
• Gently pull down the lower eyelid to create a small pocket.
• Squeeze the bottle and allow the prescribed number of drops to fall into the pocket.
• Close your eyes gently for a few seconds to allow the medication to spread evenly.
• Avoid touching the tip of the bottle to any surface to prevent contamination.

Mechanism of Action

Chlorocol Plus combines two active ingredients with different mechanisms of action to provide a comprehensive treatment approach:

• Chloramphenicol is an antibiotic that works by inhibiting the growth of bacteria responsible for eye infections. It interferes with the production of essential proteins required for bacterial survival, thereby halting their growth and reproduction.
• Dexamethasone belongs to a class of medications called corticosteroids. It helps reduce inflammation by suppressing the immune response and inhibiting the release of inflammatory substances in the eye.

Side Effects

Common side effects may include:

• Temporary stinging or burning sensation in the eyes
• Blurred vision
• Eye irritation or redness

Serious side effects are rare, but if you experience any of the following, contact your healthcare provider immediately:

• Severe eye pain or discomfort
• Worsening eye inflammation or redness
• Vision changes
• Allergic reactions such as rash, itching, or swelling

Drug Interactions

inform your healthcare provider about all the medications you are taking, including over-the-counter drugs, herbal supplements, and vitamins. Some medications may interact with Chlorocol Plus, potentially affecting its effectiveness or increasing the risk of side effects. Common drug interactions may include:

• Other eye medications or ointments
• Certain antibiotics, such as tetracyclines
• Antiviral medications, such as acyclovir

To ensure your safety and the effectiveness of the treatment, inform your healthcare provider about all your current medications before starting Chlorocol Plus.

Precautions

Before using Chlorocol Plus, consider the following precautions:

• Inform your healthcare provider if you have any known allergies or sensitivities to medications, especially chloramphenicol, dexamethasone, or any other ingredients in the eye drops.
• If you have a history of certain eye conditions, such as glaucoma or cataracts, or if you have had any recent eye surgery, inform your healthcare provider before using Chlorocol Plus.
• Do not wear contact lenses while using Chlorocol Plus, as it may cause discomfort or affect the fit of the lenses. Contact lenses can be reinserted 15 minutes after instilling the eye drops.
• Avoid touching the tip of the bottle to any surface to prevent contamination.

Storage

To maintain the effectiveness and safety of Chlorocol Plus, store it properly. Keep the bottle tightly closed when not in use, and store it at room temperature, away from direct sunlight and moisture. Do not freeze the medication. Keep it out of the reach of children and pets.

Patient Tips

Here are some additional tips to maximize the benefits of Chlorocol Plus:

• Complete the full course of treatment as prescribed by your healthcare provider, even if your symptoms improve.
• Avoid touching your eyes with dirty hands to prevent the spread of infections or further irritation.
• If you are using other eye medications or ointments, wait at least 5 minutes between applying different products unless otherwise instructed by your healthcare provider.
• If you experience any persistent or worsening side effects, contact your healthcare provider for further guidance.
• Attend follow-up appointments as scheduled to monitor your progress and ensure the appropriate management of your eye condition.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Chloramphenicol: antibiotic to treat bacterial infections (NHS UK) [Accessed 26 Jun. 2024] (online) Available at:
• Boots Infected Eyes 1%w/w Eye Ointment (Health Professionals SmPC) Available at:
• Chloramphenicol (Drugs.com) [Accessed 4 Jun. 2024] (online) Available at:
• chloramphenicol (ophth) solution (RX) [Accessed 13 Jun. 2024] (online) Available at:
• Chloramphenicol Injection (MedlinePlus) [Accessed 24 Jun. 2024] (online) Available at:
• Ingall D, Sherman JD. Chloramphenicol. Pediatr Clin North Am. 1968 Feb;15(1):57-72. doi: 10.1016/s0031-3955(16)32088-0. [Accessed 18 Jun. 2024] Available at: