Demfo 240mg Capsule

Introduction

Demfo is a prescription medication that contains the active ingredient Dimethyl fumarate. It is available under the brand name Demfo. This medication is primarily used for the treatment of multiple sclerosis, a chronic autoimmune disease that affects the central nervous system.

Uses

Demfo is prescribed to patients with relapsing forms of multiple sclerosis, including relapsing-remitting multiple sclerosis and active secondary progressive multiple sclerosis. It helps reduce the frequency and severity of relapses, as well as slow down the progression of the disease.

Dosage and Administration

The recommended dosage of Demfo is 240 mg taken orally twice daily with or without food. The capsules should be swallowed whole and should not be crushed, chewed, or opened. Follow the instructions provided by your healthcare professional regarding the timing and frequency of doses.

Mechanism of Action

Demfo works by modulating the immune system and reducing inflammation in the central nervous system. It is thought to activate a specific pathway that leads to the production of anti-inflammatory substances, thereby reducing the immune response that damages the nerves in multiple sclerosis.

Side Effects

Common side effects may include flushing, stomach upset, and diarrhea. These side effects are usually mild and may improve over time. However, if they persist or worsen, consult your healthcare professional.

In some cases, Demfo may cause more serious side effects. These may include a decrease in white blood cell count, liver problems, and allergic reactions. If you experience any severe or persistent side effects, such as unexplained bruising, yellowing of the skin or eyes, or difficulty breathing, seek immediate medical attention.

Drug Interactions

Demfo may interact with certain medications, including drugs that affect the immune system or those that are metabolized by specific enzymes in the liver. Inform your healthcare professional about all the medications you are currently taking, including prescription, over-the-counter, and herbal medications, to avoid any potential interactions.

Precautions

Before starting Demfo, inform your healthcare professional about any allergies, medical conditions, or medications you are taking. This medication may not be suitable for everyone, and certain precautions should be taken. Discuss the risks and benefits of this medication with your healthcare professional.

Demfo is contraindicated in patients with known hypersensitivity to Dimethyl fumarate or any of the inactive ingredients in the formulation. Avoid using Demfo if you have severe liver disease or a history of progressive multifocal leukoencephalopathy (PML).

Storage

Patient Tips

• Follow the dosage instructions provided by your healthcare professional and take Demfo as directed.
• It may take some time for the medication to show its full effects. Be patient and continue taking it regularly.
• If you miss a dose, take it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and resume your regular dosing schedule.
• If you have any concerns or questions about your treatment, do not hesitate to reach out to your healthcare professional.
• Keep all your appointments for monitoring and follow-up with your healthcare professional to ensure the medication is working effectively and to address any concerns that may arise.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Ferrous fumarate: medicine to treat iron deficiency anaemia (NHS UK) [Accessed 17 Jun. 2024] (online) Available at:
• Dimethyl fumarate 120 mg Gastro-resistant hard Capsules (Health Professionals SmPC) Available at:
• Dimethyl fumarate (Drugs.com) [Accessed 30 Jun. 2024] (online) Available at:
• dimethyl fumarate 120 mg capsule,delayed release multiple sclerosis agents, general (RX) [Accessed 20 Jun. 2024] (online) Available at:
• Dimethyl Fumarate (MedlinePlus) [Accessed 17 Jun. 2024] (online) Available at:
• Okuda DT, Kantarci O, Lebrun-Frénay C, Sormani MP, Azevedo CJ, Bovis F, Hua LH, Amezcua L, Mowry EM, Hotermans C, Mendoza J, Walsh JS, von Hehn C, Vargas WS, Donlon S, Naismith RT, Okai A, Pardo G, Repovic P, Stüve O, Siva A, Pelletier D. Dimethyl Fumarate Delays Multiple Sclerosis in Radiologically Isolated Syndrome. Ann Neurol. 2023 Mar;93(3):604-614. doi: 10.1002/ana.26555. Epub 2022 Dec 10. [Accessed 12 Jun. 2024] Available at: