Dexa SR Capsule

Introduction

Dexa SR is a prescription medication that contains two active ingredients: Domperidone and Dexrabeprazole. Domperidone is a medication that helps to relieve symptoms such as nausea, vomiting, bloating, and discomfort caused by certain stomach disorders. Dexrabeprazole is a proton pump inhibitor that reduces the amount of acid produced in the stomach. Together, these ingredients work to alleviate symptoms and manage conditions related to stomach disorders.

Uses

Dexa SR is commonly prescribed for the treatment of conditions such as:

• Gastroesophageal reflux disease (GERD): a condition where stomach acid flows back into the esophagus, causing heartburn and other symptoms.
• Dyspepsia: a term used to describe pain or discomfort in the upper abdomen, often associated with indigestion.
• Gastritis: inflammation of the stomach lining, which can cause pain, nausea, and vomiting.
• Peptic ulcers: open sores that develop on the lining of the stomach or the upper part of the small intestine.

Note that Dexa SR should only be used under the guidance and supervision of a healthcare professional.

Dosage and Administration

The dosage of Dexa SR may vary depending on the specific condition being treated and the individual patient’s needs. Follow the instructions provided by your healthcare provider. Typically, the recommended dose is one capsule taken orally before meals, usually twice a day.

Swallow the capsule whole and not crush or chew it, as this may affect the way the medication is released in the body. If you have difficulty swallowing the capsule, please consult your healthcare provider for alternative options.

Mechanism of Action

Domperidone, one of the active ingredients in Dexa SR, works by blocking dopamine receptors in the brain and gut. This action helps to increase the movement and contractions of the stomach and intestines, thereby promoting better digestion and reducing symptoms such as nausea and vomiting.

Dexrabeprazole, the other active ingredient, belongs to a class of medications called proton pump inhibitors. It works by inhibiting the enzyme in the stomach wall that produces acid. By reducing the amount of acid in the stomach, Dexrabeprazole helps to alleviate symptoms associated with conditions like GERD and peptic ulcers.

Side Effects

Common side effects may include:

• Headache
• Dizziness
• Dry mouth
• Diarrhea
• Abdominal pain or discomfort

If any of these side effects persist or worsen, consult your healthcare provider for further guidance.

In rare cases, more serious side effects may occur. These can include:

• Irregular heartbeat
• Severe allergic reactions (rash, itching, swelling)
• Difficulty breathing or swallowing
• Unusual tiredness or weakness
• Dark urine or pale stools

If you experience any of these serious side effects, seek immediate medical attention.

Drug Interactions

Dexa SR may interact with other medications, including prescription drugs, over-the-counter medications, and herbal supplements. Some common drug interactions include:

• Antifungal medications (e.g., ketoconazole, itraconazole)
• Antibiotics (e.g., clarithromycin, erythromycin)
• HIV protease inhibitors (e.g., ritonavir)
• Antidepressants (e.g., fluoxetine, sertraline)

inform your healthcare provider about all the medications and supplements you are currently taking to avoid potential interactions. They can provide guidance on the appropriate use of Dexa SR in conjunction with other medications.

Precautions

Before starting Dexa SR, inform your healthcare provider about any pre-existing medical conditions, allergies, or sensitivities you may have. They will assess whether this medication is suitable for you and provide necessary precautions or alternative treatment options if needed.

Some important precautions to consider include:

• Contraindications: Dexa SR should not be used in individuals who have a known allergy to any of its active ingredients or who have a history of an allergic reaction to similar medications.
• Pregnancy and breastfeeding: If you are pregnant, planning to become pregnant, or breastfeeding, consult your healthcare provider before using this medication. They will weigh the potential benefits against any potential risks to you and your baby.
• Liver or kidney problems: Individuals with liver or kidney problems may require special monitoring or adjustments to the dosage of Dexa SR. Your healthcare provider will determine the appropriate course of action based on your specific condition.

Storage

Dexa SR should be stored at room temperature, away from excessive heat, moisture, and light. Keep the medication out of reach of children and pets. Do not use this medication if it has passed the expiration date or if the packaging is damaged.

Patient Tips

Here are some additional tips to help you use Dexa SR effectively and safely:

• Take the medication as prescribed by your healthcare provider. Do not increase or decrease the dosage without their guidance.
• maintain a healthy lifestyle and follow a balanced diet while using Dexa SR.
• If you have any questions or concerns about the medication or its use, do not hesitate to consult your healthcare provider or pharmacist.
• If you miss a dose, take it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Domperidone: anti-sickness medicine for nausea and vomiting (NHS UK) [Accessed 10 Jun. 2024] (online) Available at:
• Domperidone 10 mg film-coated tablets (Health Professionals SmPC) Available at:
• Domperidone (Drugs.com) [Accessed 4 Jun. 2024] (online) Available at:
• Rabeprazole (MedlinePlus) [Accessed 29 Jun. 2024] (online) Available at:
• Lespessailles E, Toumi H. Proton Pump Inhibitors and Bone Health: An Update Narrative Review. Int J Mol Sci. 2022 Sep 14;23(18):10733. doi: 10.3390/ijms231810733. [Accessed 11 Jun. 2024] Available at: