Diabetrol SR Tablet

Introduction

Diabetrol SR is a prescription medication that combines two active ingredients: Glibenclamide and Metformin. It is commonly used to manage type 2 diabetes mellitus when diet and exercise alone are not sufficient to control blood sugar levels.

Uses

Diabetrol SR is primarily prescribed to treat type 2 diabetes mellitus. It is indicated for patients whose blood sugar levels are not well controlled by diet and exercise alone. It helps to lower blood sugar levels by increasing the release of insulin from the pancreas and improving the body’s sensitivity to insulin.

Dosage and Administration

The dosage of Diabetrol SR will depend on your individual needs and medical condition. Follow your healthcare provider’s instructions regarding the dosage and administration of this medication. Typically, the initial dose is one tablet taken once or twice daily with meals. Your doctor may adjust the dose as needed to achieve optimal blood sugar control.

Mechanism of Action

Diabetrol SR contains two active ingredients, Glibenclamide and Metformin, which work together to help manage type 2 diabetes mellitus. Glibenclamide stimulates the release of insulin from the pancreas, which helps to lower blood sugar levels. Metformin improves insulin sensitivity and reduces the amount of glucose produced by the liver.

Side Effects

Common side effects may include nausea, diarrhea, abdominal discomfort, and low blood sugar levels (hypoglycemia). These side effects are usually mild and go away on their own. However, if you experience any serious side effects such as severe allergic reactions, chest pain, or difficulty breathing, seek immediate medical attention.

Drug Interactions

Diabetrol SR may interact with certain medications, potentially affecting their effectiveness or increasing the risk of side effects. Inform your healthcare provider about all the medications you are currently taking, including prescription, over-the-counter, and herbal products. Some common drug interactions include:

• Beta-blockers: May mask the symptoms of low blood sugar levels.
• Thiazide diuretics: May increase the risk of high blood sugar levels.
• Warfarin: May increase the risk of bleeding.

This is not an exhaustive list, and other drug interactions may occur. Always consult your healthcare provider for personalized advice.

Precautions

Before taking Diabetrol SR, inform your healthcare provider about any existing medical conditions, allergies, or medications you are currently taking. Certain precautions should be taken into consideration, including:

• Hypoglycemia: Diabetrol SR may cause low blood sugar levels. Monitor your blood sugar levels regularly and be aware of the signs and symptoms of hypoglycemia.
• Liver or kidney problems: Diabetrol SR should be used with caution in patients with liver or kidney problems, as it may affect their function.
• Pregnancy and breastfeeding: Diabetrol SR should be used with caution during pregnancy and breastfeeding. Consult your healthcare provider for personalized advice.

Storage

Diabetrol SR should be stored at room temperature, away from moisture and direct sunlight. Keep it out of reach of children and pets. Do not use the medication if it has expired or if the packaging is damaged.

Patient Tips

Here are some additional tips to help you manage your diabetes while taking Diabetrol SR:

• Follow your healthcare provider’s instructions: Take the medication as prescribed and follow your doctor’s advice on diet, exercise, and monitoring your blood sugar levels.
• Monitor your blood sugar levels: Regularly check your blood sugar levels as directed by your healthcare provider. This will help you gauge the effectiveness of the medication and make any necessary adjustments to your treatment plan.
• Maintain a healthy lifestyle: Adopt a healthy diet, engage in regular physical activity, and manage stress to support overall diabetes management.
• Be aware of the signs of low blood sugar: Learn to recognize the symptoms of low blood sugar, such as dizziness, sweating, and confusion. Always carry a source of glucose (such as glucose tablets or juice) in case of emergencies.
• Keep appointments with your healthcare provider: Regular check-ups are important to monitor your progress and make any necessary adjustments to your treatment plan.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Metformin: a medicine to treat type 2 diabetes (NHS UK) [Accessed 10 Jun. 2024] (online) Available at:
• AMGLIDIA 0.6 mg/mL oral suspension with 5 mL oral syringe (Health Professionals SmPC) Available at:
• Glibenclamide (International database) (Drugs.com) [Accessed 19 Jun. 2024] (online) Available at:
• metformin (RX) [Accessed 21 Jun. 2024] (online) Available at:
• Glyburide (MedlinePlus) [Accessed 11 Jun. 2024] (online) Available at:
• Zubov A, Muruzheva Z, Tikhomirova M, Karpenko M. Glibenclamide as a neuroprotective antidementia drug. Arch Physiol Biochem. 2022 Dec;128(6):1693-1696. doi: 10.1080/13813455.2020.1789170. Epub 2020 Jul 11. [Accessed 3 Jun. 2024] Available at: