Dokay Eye/Ear Drop

Introduction

Dokay is a prescription medication that combines three active ingredients: Chloramphenicol, Dexamethasone, and Polymyxin B. It is commonly used to treat various ear infections and inflammation.

Uses

Dokay is primarily prescribed for the treatment of bacterial ear infections, such as otitis externa (outer ear infection) and otitis media (middle ear infection). It can also be used to reduce inflammation and relieve symptoms associated with these infections, such as pain, swelling, and discharge.

Dosage and Administration

The recommended dosage of Dokay may vary depending on the severity of the infection and the individual patient’s response to treatment. Follow the instructions provided by your healthcare professional. Typically, the ear drops are instilled into the affected ear(s) 2 to 3 times daily. Before using the ear drops, ensure that the affected ear is clean and dry. Gently tilt your head to the side and instill the prescribed number of drops into the ear canal. After instilling the drops, keep your head tilted for a few minutes to allow the medication to reach the affected area. Avoid touching the dropper tip to any surface to prevent contamination.

Mechanism of Action

Dokay contains three active ingredients that work together to combat ear infections. Chloramphenicol is an antibiotic that inhibits bacterial protein synthesis, thereby preventing the growth and spread of bacteria. Dexamethasone is a corticosteroid that helps reduce inflammation and suppresses the immune response in the affected area. Polymyxin B is a polypeptide antibiotic that disrupts the integrity of bacterial cell membranes, leading to cell death.

Side Effects

Common side effects may include temporary burning or stinging sensation in the ear, itching, or redness. These side effects are usually mild and subside on their own. However, if you experience any persistent or severe side effects, such as severe pain, hearing loss, or signs of an allergic reaction (e.g., rash, swelling), seek medical attention immediately.

Drug Interactions

Dokay may interact with other medications. Inform your healthcare professional about all the medications you are currently taking, including prescription drugs, over-the-counter medications, and herbal supplements. Some medications may interact with Dokay, potentially affecting its effectiveness or increasing the risk of side effects. Your healthcare professional will be able to determine if any drug interactions are relevant to your specific situation.

Precautions

Before using Dokay, inform your healthcare professional about any known allergies or sensitivities to medications. Additionally, let your healthcare professional know if you have any other medical conditions, such as a perforated eardrum, as this may affect the suitability of this medication for you. Dokay should not be used in certain situations, such as if you are pregnant or breastfeeding, unless explicitly recommended by your healthcare professional. It is always essential to follow your healthcare professional’s advice and instructions regarding the use of this medication.

Storage

Dokay should be stored at room temperature, away from direct sunlight and heat sources. Keep the medication out of reach of children and pets. Do not use the ear drops if they have expired or if the liquid has changed color or consistency. If in doubt, consult your pharmacist for proper disposal.

Patient Tips

Here are a few tips to help you make the most out of your treatment with Dokay:

• Follow the prescribed dosage and administration instructions provided by your healthcare professional.
• If you experience any discomfort or pain during the administration of the ear drops, consult your healthcare professional for guidance.
• Do not share your medication with others, even if they have similar symptoms. Each individual may require a specific treatment plan.
• Avoid touching the dropper tip to any surface to prevent contamination.
• If you miss a dose, apply it as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and continue with your regular dosing schedule.
• If your symptoms do not improve or worsen after a few days of treatment, contact your healthcare professional for further evaluation.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Chloramphenicol: antibiotic to treat bacterial infections (NHS UK) [Accessed 26 Jun. 2024] (online) Available at:
• Boots Infected Eyes 1%w/w Eye Ointment (Health Professionals SmPC) Available at:
• Chloramphenicol (Drugs.com) [Accessed 4 Jun. 2024] (online) Available at:
• chloramphenicol (ophth) solution (RX) [Accessed 13 Jun. 2024] (online) Available at:
• Chloramphenicol Injection (MedlinePlus) [Accessed 24 Jun. 2024] (online) Available at:
• Ingall D, Sherman JD. Chloramphenicol. Pediatr Clin North Am. 1968 Feb;15(1):57-72. doi: 10.1016/s0031-3955(16)32088-0. [Accessed 18 Jun. 2024] Available at: