Drotel DS Tablet

Introduction

Drotel DS is a prescription medication that contains the active ingredient Drotaverine. It is available under the brand name Drotel DS. This medication is primarily used to provide relief from spasms and pain associated with various conditions.

Uses

Drotel DS is prescribed to treat a range of conditions that cause smooth muscle spasms, such as:

• Abdominal pain: It can help relieve spasms in the abdominal area, providing relief from conditions like irritable bowel syndrome (IBS) and gastrointestinal disorders.
• Menstrual pain: Drotel DS is often used to alleviate abdominal cramps and pain during menstruation.
• Urinary tract disorders: It may be prescribed to relieve spasms in the urinary tract, helping to alleviate pain and discomfort associated with conditions like urinary tract infections and kidney stones.
• Other conditions: In some cases, healthcare professionals may prescribe Drotel DS for other conditions characterized by smooth muscle spasms.

Dosage and Administration

The dosage of Drotel DS should be determined by a healthcare professional based on individual patient factors, such as the severity of the condition and the patient’s response to treatment. Follow the prescribed dosage instructions provided by your healthcare provider.

Typically, the recommended dosage for adults is one tablet, taken orally, two to three times a day. It is recommended to take the tablet with a glass of water, preferably after a meal. The exact dosage and duration of treatment may vary depending on the condition being treated.

Please note that the dosage and administration instructions provided here are a general guideline. Always consult your healthcare provider for personalized dosage recommendations.

Mechanism of Action

Drotel DS contains the active ingredient Drotaverine, which belongs to a class of medications called antispasmodics. It works by relaxing the smooth muscles in the body, including those in the gastrointestinal tract, urinary tract, and blood vessels. By doing so, it helps to relieve spasms, reduce pain, and improve blood flow to affected areas.

Side Effects

Common side effects that may occur include:

• Nausea
• Dizziness
• Headache
• Dry mouth
• Upset stomach

If any of these side effects persist or worsen. Inform your healthcare provider.

In rare cases, serious side effects may occur. If you experience any of the following, seek immediate medical attention:

• Allergic reaction (e.g., rash, itching, swelling, severe dizziness)
• Rapid heartbeat
• Difficulty breathing
• Chest pain

Drug Interactions

Drotel DS may interact with certain medications, which can affect its effectiveness or increase the risk of side effects. Inform your healthcare provider about all the medications you are currently taking, including prescription drugs, over-the-counter medications, and herbal supplements.

Some common drug interactions to be aware of include:

• Cimetidine: Concurrent use with Drotel DS may increase the risk of side effects.
• Ketoconazole: Co-administration with Drotel DS may lead to increased levels of Drotaverine in the body.
• Warfarin: Drotel DS may interfere with the anticoagulant effects of Warfarin, increasing the risk of bleeding.

This is not an exhaustive list of drug interactions. Consult your healthcare provider or pharmacist for a comprehensive list of potential drug interactions.

Precautions

Before taking Drotel DS, inform your healthcare provider about any pre-existing medical conditions, including allergies and other medications you are taking. Certain precautions should be taken into consideration, including:

• Contraindications: Drotel DS is contraindicated in individuals with known hypersensitivity to Drotaverine or any other components of the medication.
• Pregnancy and breastfeeding: consult your healthcare provider before taking this medication if you are pregnant, planning to become pregnant, or breastfeeding.
• Liver or kidney impairment: Drotel DS should be used with caution in individuals with liver or kidney impairment, as the dosage may need to be adjusted.
• Driving and operating machinery: Drotel DS may cause dizziness or drowsiness. Avoid driving or operating machinery if you experience these side effects.

Storage

Patient Tips

• Take Drotel DS exactly as prescribed by your healthcare provider. Do not exceed the recommended dosage.
• If you miss a dose, take it as soon as you remember. However, if it is close to your next scheduled dose, skip the missed dose and resume your regular dosing schedule.
• Do not stop taking Drotel DS without consulting your healthcare provider, even if you feel better. Abruptly discontinuing the medication may lead to a recurrence of symptoms.
• Inform your healthcare provider about any side effects or concerns you may have while taking Drotel DS.
• If you have any questions or need further information about the medication, consult your healthcare provider or pharmacist.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Drotaverine (International database) (Drugs.com) [Accessed 5 Jun. 2024] (online) Available at:
• Kanbur AS, Agarwal A, Rokade ML. Drotaverine-induced priapism. Indian J Urol. 2021 Jan-Mar;37(1):90-91. doi: 10.4103/iju.IJU_240_20. Epub 2021 Jan 1. [Accessed 22 Jun. 2024] Available at:
• Pavel IZ, Heller L, Sommerwerk S, Loesche A, Al-Harrasi A, Csuk R. Drotaverine – a Concealed Cytostatic! Arch Pharm (Weinheim). 2017 Jan;350(1). doi: 10.1002/ardp.201600289. Epub 2016 Nov 23. [Accessed 12 Jun. 2024] Available at:
• Ibrahim MI, Alzeeniny HA, Ellaithy MI, Salama AH, Abdellatif MA. Drotaverine to improve progression of labor among nulliparous women. Int J Gynaecol Obstet. 2014 Feb;124(2):112-7. doi: 10.1016/j.ijgo.2013.08.013. Epub 2013 Nov 7. [Accessed 19 Jun. 2024] Available at: